Pharmacokinetics and pharmacodynamics of metformin in healthy subjects and patients with noninsulin‐dependent diabetes mellitus

NC Sambol, J Chiang, M O'Conner… - The Journal of …, 1996 - Wiley Online Library
… the pharmacokinetic parameters between these two groups. … In this study, both
pharmacokinetics and pharmacodynamics (… with NIDDM and healthy subjects, male and female …

[HTML][HTML] Pharmacokinetics and pharmacodynamics of lysergic acid diethylamide in healthy subjects

PC Dolder, Y Schmid, AE Steuer, T Kraemer… - … pharmacokinetics, 2017 - Springer
… between plasma exposure to LSD and the pharmacodynamic effects at corresponding times…
in 24 and 16 healthy subjects, respectively. The pharmacokinetic data and concentration–…

The pharmacokinetics and pharmacodynamics of lignocaine and MEGX in healthy subjects

AH Thomson, HL Elliott, AW Kelman… - … of pharmacokinetics …, 1987 - Springer
… This study examined the pharmacokinetics and pharmacodynamics of lignocaine and
MEGX in eight healthy male volunteers given lignocaine HCl 120mg, MEGX HCl 120 mg, …

Variability in the pharmacokinetics and pharmacodynamics of low dose aspirin in healthy male volunteers

IH Benedek, AS Joshi, HJ Pieniaszek… - The Journal of …, 1995 - Wiley Online Library
healthy, young male subjects and to assess the intra‐ and inter‐subject variability of ASA
pharmacokinetics … Ten subjects each received a single, open‐label, oral 80‐mg ASA dose on …

Pharmacokinetics and pharmacodynamics of γ‐hydroxybutyrate in healthy subjects

ME Liechti, BB Quednow, E Liakoni… - British journal of …, 2016 - Wiley Online Library
… assessed the pharmacokinetics and pharmacodynamics of two … of healthy subjects. The
study showed first-order elimination for two different moderate doses of GHB in healthy subjects, …

Pharmacokinetics and pharmacodynamics of irbesartan in healthy subjects

MR Marino, K Langenbacher, NF Ford… - The Journal of …, 1998 - Wiley Online Library
The safety, pharmacokinetics, and pharmacodynamics of single and multiple doses of the
angiotensin II (AII) AT 1 blocker irbesartan were assessed in healthy subjects. In this single‐…

AZD3293: pharmacokinetic and pharmacodynamic effects in healthy subjects and patients with Alzheimer's disease

G Cebers, RC Alexander… - Journal of …, 2017 - content.iospress.com
… Here we report the favorable findings of the first Phase I clinical trials of AZD3293 in healthy
subjects and patients with mild to moderate Alzheimer’s disease. AZD3293 was given as an …

Pharmacokinetics and pharmacodynamics of CHF5074 after short-term administration in healthy subjects

BP Imbimbo, E Frigerio, M Breda… - Alzheimer Disease & …, 2013 - journals.lww.com
… We evaluated the safety, tolerability, pharmacokinetics, and preliminary pharmacodynamics
… to young healthy male subjects. We also evaluated the pharmacokinetics of CHF5074 in …

Effect of St John's wort and ginseng on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects

X Jiang, KM Williams, WS Liauw… - British journal of …, 2004 - Wiley Online Library
Aim The aim of this study was to investigate the effect of St John's wort and ginseng on the
pharmacokinetics and pharmacodynamics of warfarin. Methods This was an open‐label, three…

Pharmacokinetics and pharmacodynamics of sitagliptin, an inhibitor of dipeptidyl peptidase IV, in healthy subjects: results from two randomized, double‐blind, placebo …

GA Herman, C Stevens, K Van Dyck… - Clinical …, 2005 - Wiley Online Library
… Moreover, the absence of an effect of sitagliptin on glycemic parameters in healthy
subjects in this study, together with the observed lack of effect on signs and symptoms of …