Epigenetic-related therapeutic challenges in cardiovascular disease
C Schiano, MT Vietri, V Grimaldi, A Picascia… - Trends in …, 2015 - cell.com
… challenges for therapeutic strategies in CVDs. We discuss the main epigenetic mechanisms
involved in atherosclerosis, coronary heart disease (CHD), HF, MI, and cardiac hypertrophy. …
involved in atherosclerosis, coronary heart disease (CHD), HF, MI, and cardiac hypertrophy. …
Diagnostic and therapeutic challenges in patients with coexistent chronic obstructive pulmonary disease and chronic heart failure
TH Le Jemtel, M Padeletti, S Jelic - Journal of the American College of …, 2007 - jacc.org
Chronic obstructive pulmonary disease (COPD) and heart failure (CHF) are common conditions.
The prevalence of COPD ranges from 20% to 30% in patients with CHF. The diagnosis …
The prevalence of COPD ranges from 20% to 30% in patients with CHF. The diagnosis …
[HTML][HTML] Hypertensive Heart Disease—From Pathophysiology to Therapeutical Challenges
AS Vischer, T Burkard - Journal of Clinical Medicine, 2022 - mdpi.com
… The prevalence of hypertensive heart disease (HHD) has increased over the last … this disease
[1]. Furthermore, AHT remains the most important risk factor for ischemic heart disease with …
[1]. Furthermore, AHT remains the most important risk factor for ischemic heart disease with …
Anti-inflammatory therapy in chronic disease: challenges and opportunities
… In these diseases, the precise identity of the … in therapeutically targeting the inflammatory
response. Although there has been success with anti-inflammatory therapy in chronic diseases …
response. Although there has been success with anti-inflammatory therapy in chronic diseases …
Toward microrna–based therapeutics for heart disease: The sense in antisense
E Van Rooij, WS Marshall, EN Olson - Circulation research, 2008 - Am Heart Assoc
… modulation of disease mechanisms. Here, we summarize current knowledge of the roles of
miRNAs in heart disease and consider the advantages and potential challenges of microRNA…
miRNAs in heart disease and consider the advantages and potential challenges of microRNA…
[HTML][HTML] miRNAS in cardiovascular diseases: potential biomarkers, therapeutic targets and challenges
S Zhou, J Jin, J Wang, Z Zhang, JH Freedman… - Acta Pharmacologica …, 2018 - nature.com
… Heart failure is the final manifestation of CVD and cardiac injury, as well as less common but
important etiologies including cardiomyopathies, valvular heart disease… -based therapeutics …
important etiologies including cardiomyopathies, valvular heart disease… -based therapeutics …
RNA therapeutics in cardiovascular disease
T Lucas, A Bonauer, S Dimmeler - Circulation research, 2018 - Am Heart Assoc
… Whether lncRNAs can be therapeutically targeted in a comparable manner as … challenges
in using noncoding RNAs as therapeutic targets for the treatment of cardiovascular diseases. …
in using noncoding RNAs as therapeutic targets for the treatment of cardiovascular diseases. …
Hypertensive heart disease and myocardial fibrosis: How traditional Chinese medicine can help addressing unmet therapeutical needs
M Liu, X Long, J Xu, M Chen, H Yang, X Guo… - Pharmacological …, 2022 - Elsevier
… for the occurrence and development of ventricular dilatation and heart failure. MF is the
pathological basis of hypertensive heart disease (HHD), and blood pressure control is the key to …
pathological basis of hypertensive heart disease (HHD), and blood pressure control is the key to …
The therapeutical effect of Chinese medicine for the treatment of atherosclerotic coronary heart disease
J Zhang, H Meng, Y Zhang, X Zhang… - Current …, 2017 - ingentaconnect.com
… Abstract: Coronary heart disease (CHD) is the leading cause … Finally, challenges and
opportunities facing application of … AS is the main cause of coronary heart disease (CHD), which …
opportunities facing application of … AS is the main cause of coronary heart disease (CHD), which …
[HTML][HTML] MicroRNAs: powerful new regulators of heart disease and provocative therapeutic targets
E Van Rooij, EN Olson - The Journal of clinical investigation, 2007 - Am Soc Clin Investig
… A major challenge for the future will be to identify the mRNA targets of the … for therapeutically
exploiting the biology of miRNAs in the settings of congenital and acquired heart disease, …
exploiting the biology of miRNAs in the settings of congenital and acquired heart disease, …