… consideration when prescribing β-AR antagonists in heart failure. … β-AR-mediated signal
transduction in failing heart contribute to the beneficial effects of β-AR antagonists in heart failure…

… Carvedilol is currently the only β-blocker approved for treatment of chronic heart failure in
the United States and most other countries. There have been 1748 subjects enrolled in 8 …

… the development of β-blocker therapy in heart failure, as when … clinically important worsening
of heart failure, as stated in a … to β-blockers being generally contraindicated in heart failure, …

… , following long-term treatment with 0-adrenoceptor antagonists, occurs in a subtype … heart
failure undergoing elective coronary bypass grafting, different /?-adrenoceptor antagonists …

… with HF, prescription of a β-adrenoceptor antagonist may raise … of published data, β-adrenoceptor
antagonists are under-… and tolerability of β-adrenoceptor antagonist therapy in elderly …

… evidence that the failing human heart exhibited β-adrenergic receptor downregulation and
… consistent with the results of other large β-blocker trials just reported in these populations. In …

… -adrenoceptor blockers in chronic heart failure: the known adverse effects of chronic sympathetic
activation in heart failure… of b-adrenoceptor blockers in heart failure and practical issues …

… The experience summarized in this review indicates that, as do ACE inhibitors, [3-blockers
can alleviate the symptoms of heart failure, improve clinical status, and enhance the overall …

… Similarly, β-AR antagonist treatment of heart failure patients returnedthe increased expression
of Gαi to near normal levels(95). Changes in Gαi2protein and mRNA content following …

… data regarding the use of fl-adrenergic blockers for the treatment of congestive heart … of
P-blockers on contractility and relaxation. We examined 15 patients with congestive heart failure …