Autonomic regulation therapy in heart failure

U Buckley, K Shivkumar, JL Ardell - Current heart failure reports, 2015 - Springer
Heart failure continues to have a high mortality rate, despite … of heart failure, this review
will specifically focus on autonomic-modulating device therapy in the setting of heart failure with …

The autonomic nervous system and heart failure

VG Florea, JN Cohn - Circulation research, 2014 - Am Heart Assoc
… This technique has been used in clinical neurophysiology to evaluate the neural
mechanisms of autonomic regulation, motor control, and sensory functions in physiological and …

Assessment of autonomic regulation in chronic congestive heart failure by heart rate spectral analysis

JP Saul, Y Arai, RD Berger, LS Lilly, WS Colucci… - The American journal of …, 1988 - Elsevier
… Neurohumoral modulation of cardiovascular function is an important component of the
hemodynamic alterations in patients with chronic congestive heart failure (CHF). Analysts of heart

[HTML][HTML] Heart failure as an autonomic nervous system dysfunction

T Kishi - Journal of cardiology, 2012 - Elsevier
… that heart failure is a complex syndrome with an autonomic nervous system dysfunction, and
that the autonomic … may be due to an up-regulation in central antioxidative mechanisms and …

Impact of autonomic regulation therapy in patients with heart failure: ANTHEM-HFrEF pivotal study design

MA Konstam, JE Udelson, J Butler, HU Klein… - … : Heart Failure, 2019 - Am Heart Assoc
… of Heart Failure with Reduced Ejection Fraction) pivotal study is an adaptive, open-label,
randomized, controlled study evaluating whether autonomic regulationautonomic regulation

Autonomic regulation therapy to enhance myocardial function in heart failure patients: the ANTHEM‐HFpEF study

LA DiCarlo, I Libbus, HU Kumar, S Mittal… - … heart failure, 2018 - Wiley Online Library
… Approximately half of the patients presenting with new‐onset heart failure (HF) have HF with
… Beneficial effects of autonomic regulation therapy (ART) using vagus nerve stimulation (VNS…

[HTML][HTML] Extended follow-up of patients with heart failure receiving autonomic regulation therapy in the ANTHEM-HF study

RK Premchand, K Sharma, S Mittal, R Monteiro… - … of cardiac failure, 2016 - Elsevier
… Chronic heart failure (HF) is characterized by autonomic dysfunction, including excessive
sympathetic activation and concomitant parasympathetic withdrawal.1, 2 This autonomic

[HTML][HTML] Autonomic regulation therapy for the improvement of left ventricular function and heart failure symptoms: the ANTHEM-HF study

L Dicarlo, I Libbus, B Amurthur, BH Kenknight… - … of cardiac failure, 2013 - Elsevier
… Therapy to Enhance Myocardial Function in Heart Failure (ANTHEM-HF) study … autonomic
regulation therapy (ART) in patients with LV dysfunction and chronic symptomatic heart failure. …

[HTML][HTML] Autonomic regulation therapy via left or right cervical vagus nerve stimulation in patients with chronic heart failure: results of the ANTHEM-HF trial

RK Premchand, K Sharma, S Mittal, R Monteiro… - … of cardiac failure, 2014 - Elsevier
… insult, the autonomic nervous system attempts to preserve cardiac output by up-regulating
These changes in autonomic regulatory control of the cardiovascular system lead to a host …

The 2021 Carl Ludwig Lecture. Unsympathetic autonomic regulation in heart failure: Patient-inspired insights

JS Floras - American Journal of Physiology-Regulatory …, 2021 - journals.physiology.org
… , heart failure also is a state of autonomic disequilibrium. A large body of evidence affirms that
autonomic disturbances are intrinsic to heart failure… of maladaptive autonomic disturbances …