Implication of cardiac remodeling in heart failure: mechanisms and therapeutic strategies

H Takano, H Hasegawa, T Nagai, I Komuro - Internal Medicine, 2003 - jstage.jst.go.jp
… molecular mechanismsof cardiac remodeling and to develop novel therapeutic strategies for
… for heart failure. In the present review, wedescribe the recent studies on cardiac remodeling

Cardiac remodeling—concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling

…, an International Forum on Cardiac Remodeling - Journal of the American …, 2000 - jacc.org
Cardiac remodeling is generally accepted as a determinant of the clinical course of heart
failure (HF)… in size, shape and function of the heart resulting from cardiac load or injury, cardiac

Role of various proteases in cardiac remodeling and progression of heart failure

AL Müller, NS Dhalla - Heart failure reviews, 2012 - Springer
cardiac remodeling [4], which is considered to be the underlying cause of heart failure. It …
involved in the process of cardiac remodeling and the occurrence of heart failure due to different …

Cardiac remodeling as a consequence and cause of progressive heart failure

K Kurrelmeyer, D Kalra, B Bozkurt, F Wang… - Clinical …, 1998 - Wiley Online Library
heart failure, very little is known about the basic mechanisms that lead to cardiac remodeling
the importance of the remodeling process during the progression of heart failure. The intent …

Cardiac remodeling and failure: from molecules to man (Part I)

PWM Fedak, S Verma, RD Weisel, RK Li - Cardiovascular Pathology, 2005 - Elsevier
… strategies for patients with congestive heart failure (CHF). Cardiac remodeling (CR) is the
restructuring and reshaping of the heart that underlies heart failure progression. CR is a major …

Imaging, biomarker, and clinical predictors of cardiac remodeling in heart failure with reduced ejection fraction

A Aimo, HK Gaggin, A Barison, M Emdin, JL Januzzi - JACC: Heart Failure, 2019 - jacc.org
Cardiac remodeling is a pivotal process in the progression of heart failure (HF). … (also
known as athlete’s heart), this is a reversible form of cardiac remodeling, as left ventricular (LV) …

Cardiac remodeling and failure: from molecules to man (Part II)

PWM Fedak, S Verma, RD Weisel, RK Li - Cardiovascular Pathology, 2005 - Elsevier
… contribute to maladaptive cardiac remodeling and the transition to heart failure. TIMP-… failing
heart may contribute to maladaptive cardiac remodeling and the progression of heart failure

Energy metabolism in cardiac remodeling and heart failure

PS Azevedo, MF Minicucci, PP Santos… - Cardiology in …, 2013 - journals.lww.com
… During heart remodeling, however, the fuel preference switches to glucose. In the earlier …
cardiac remodeling, changes in energy metabolism are considered crucial to protect the heart

The emerging role of microRNAs in cardiac remodeling and heart failure

V Divakaran, DL Mann - Circulation research, 2008 - Am Heart Assoc
… genes that are responsible for cardiac hypertrophy. However, it is not clear whether these
miRNAs contribute to the adverse cardiac remodeling that occurs in heart failure, insofar as the …

Role of microRNAs in cardiac remodeling and heart failure

VK Topkara, DL Mann - Cardiovascular drugs and therapy, 2011 - Springer
… that miRNAs modulate various aspects of the heart failure phenotype [2–7]. This … cardiac
remodeling and discusses the potential application of miRNA biology to the field of heart failure