A hallmark symptom of heart failure (HF) is exercise intolerance, typically evidenced by
excessive shortness of breath, and/or fatigue with exertion. In recent years, the physiologic …

… Although multiple therapies have been shown to lower mortality in patients with heart failure
(HF) and reduced left ventricular ejection fraction, their application in clinical practice has …

… acutely decompensated heart failure. In the last decade scientific and clinical interest has …
, but not necessarily acutely decompensated, heart failure. Recent studies have suggested long…

… In a series of 486 patients admitted to a heart failure service with low LVEF, 67% of those
with clinical evidence of decompensation appeared on initial evaluation as profile B (wet and …

… We show, using simple, universally available clinical and echocardiographic characteristics,
that the probability that heart failure with preserved ejection fraction is present can be …

… Background— A treatment gap exists between heart failure (HF) guidelines and the clinical
… clinical evidence and national guideline-recommended therapies into routine clinical …

… Evidence is accumulating that normal natriuretic peptide … heart failure are not mutually
exclusive—in heart failure … appropriate to distinguish between heart failure with normal/preserved …

… evidence from smaller trials and updated meta‐analyses have given us the chance to provide
refined recommendations in selected other areas. Further, new trial evidence … heart failure. …

… clinical practice guidelines.126-128 Nevertheless, considerable variation in the quality of
heart failure care and clinical … guidelines, this section presents evidence to show that there is …

… who fulfil diagnostic criteria for heart failure have evidence of impaired left ventricular …
patients with clinical evidence of heart failure, and indeed with echocardiographic evidence of left …