… of remodeling changes on clinical outcomes in heart failure and provides support for the
use of remodeling parameters to guide subsequent larger scale clinical investigation and to …

… Current evidence indicates that heart failure (HF) is usually a progressive condition that
begins with risk factors for cardiac dysfunction, proceeds to asymptomatic changes in cardiac …

Aims Inflammation is a central process in the pathophysiology of heart failure (HF), but trials
targeting tumour necrosis factor (TNF)‐α were largely unsuccessful. Interleukin (IL)‐6 is an …

Aim Diminished diuretic response is common in patients with acute heart failure, although a
clinically useful definition is lacking. Our aim was to investigate a practical, workable metric …

… We analysed the clinical significance of WRF in 318 consecutive patients admitted at our
institute for AHF. WRF was defined as the occurrence, at any time during the hospitalisation, of …

… Therefore, we proceeded to evaluate the clinical impact of high atrial arrhythmic burden in
a heart failure (HF) population receiving cardiac resynchronization therapy (CRT) with remote …

Background—In congestive heart failure (CHF), the prognostic significance of impaired
respiratory muscle strength has not been established. Methods and Results—Maximal …

Background— Left atrial (LA) enlargement is associated with adverse events in heart failure
with preserved ejection fraction (HFpEF). However, the role of LA mechanics (ie, LA strain …

… In previous, smaller studies of heart failure patients, the effects of … significance of atrial
fibrillation in advanced heart failure, we … in 390 consecutive patients with advanced heart failure. …

… heart failure outcome consisting of death due to heart failure or hospitalization due to worsening
heart failure… of the pathophysiology underlying the clinical heart failure in these patients. …