… of heart failure in the elderly. Previous basic, clinical, and population sciences have advanced
the modern treatment of heart failure, but … (LV) failure have not yet been fully elucidated. …

… increase in the prevalence of heart failure in the elderly. Previous basic, clinical, and population
sciences have advanced the modern treatment of heart failure. Despite extensive studies…

… To elucidate the type of DNA damage in the failing heart, we isolated cardiomyocytes after
… of heart failure remain elusive. In the present study, we identified the type of DNA damage …

… which is used as a reliable maker of oxidative DNA damage.In … cardiomyopathy (DCM),24
so we hypothesized that oxidative DNA damage would be elevated in patients with heart failure…

… DNA damage is a common signature of advanced heart failure and can be a prognostic
predictor for heart failure … of the association between DNA damage and treatment response and …

… Cre induction are associated with lethal heart failure in αMHC-MerCreMer transgenic mice.
… of a DNA damage response. Our results also indicate that the DNA damage response and …

Background: Heart failure (HF) coincides with cardiomyocyte telomere shortening. Arterial
hypertension is the most prominent risk factor for HF. Both HF and arterial hypertension are …

… DNA damage repair among HF patients. To our knowledge, this is the first study to report on
the status of oxidative stress, DNA damage and repair in end-stage heart failure … heart failure …

… the potential involvement of DNA damage and the DNA damage response (DDR) given the
role Gadd45α plays in the maintenance of genomic stability and DNA repair. We hypothesize …

… DNA damage response, we examined ATM (ataxia telangiectasia mutated) kinase, one of the
best characterized DNA damage … Our results reveal a role of the DNA damage response in …