Effect of empagliflozin in patients with heart failure across the spectrum of left ventricular ejection fraction

J Butler, M Packer, G Filippatos… - European Heart …, 2022 - academic.oup.com
… or heart failure hospitalizations in patients with heart failure … of the effect of empagliflozin on
heart failure hospitalizations … -Reduced (Empagliflozin Outcomes Trial in Heart Failure and a …

Effect of empagliflozin on the clinical stability of patients with heart failure and a reduced ejection fraction: the EMPEROR-Reduced trial

M Packer, SD Anker, J Butler, G Filippatos, JP Ferreira… - Circulation, 2021 - Am Heart Assoc
… In conclusion, in patients with heart failure and a reduced ejection fraction, empagliflozin
reduced the risk of inpatient and outpatient worsening heart failure events, benefits that were …

Effect of empagliflozin on cardiovascular and renal outcomes in patients with heart failure by baseline diabetes status: results from the EMPEROR-reduced trial

SD Anker, J Butler, G Filippatos, MS Khan, N Marx… - Circulation, 2021 - Am Heart Assoc
… the effect of the drug on renal outcomes as a major outcome variable. Empagliflozin reduced
the risk of major adverse heart failure … and safety of empagliflozin on heart failure and renal …

Effect of empagliflozin on worsening heart failure events in patients with heart failure and preserved ejection fraction: EMPEROR-preserved trial

M Packer, J Butler, F Zannad, G Filippatos, JP Ferreira… - Circulation, 2021 - Am Heart Assoc
heart failure events in patients with heart failure and an ejection fraction >40%. Furthermore,
because patients with heart failure … than heart failure, we report on the effect of empagliflozin

[HTML][HTML] Empagliflozin in heart failure with a preserved ejection fraction

SD Anker, J Butler, G Filippatos… - … England Journal of …, 2021 - Mass Medical Soc
… benefit of empagliflozin on major heart failure outcomes in patients with heart failure and a
… In addition, we show that the favorable effects in this heart failure phenotype were also seen …

Effect of empagliflozin on hemodynamics in patients with heart failure and reduced ejection fraction

M Omar, J Jensen, PH Frederiksen, C Kistorp… - Journal of the American …, 2020 - jacc.org
… This study is a separate part of the empagliflozin in heart failure patients with reduced …
the effect of empagliflozin on brain natriuretic peptide after 12 weeks of treatment and failed to …

[HTML][HTML] Cardiovascular and renal outcomes with empagliflozin in heart failure

M Packer, SD Anker, J Butler, G Filippatos… - … England Journal of …, 2020 - Mass Medical Soc
… the estimated GFR; the latter effect was accompanied by a lower risk of serious renal
outcomes. Our findings with empagliflozin can be compared with the effects of dapagliflozin in the …

Effect of empagliflozin on exercise ability and symptoms in heart failure patients with reduced and preserved ejection fraction, with and without type 2 diabetes

WT Abraham, JA Lindenfeld, P Ponikowski… - European heart …, 2021 - academic.oup.com
… The EMPERIAL (Effect of EMPagliflozin on ExeRcise ability … heArt faiLure) trials evaluated
the effects of empagliflozin on exercise ability and patient-reported outcomes in heart failure (…

Effects of empagliflozin on risk for cardiovascular death and heart failure hospitalization across the spectrum of heart failure risk in the EMPA-REG OUTCOME® trial

D Fitchett, J Butler, P van de Borne… - European heart …, 2018 - academic.oup.com
effects of empagliflozin in patients across the spectrum of HF and HF risk. Specifically, we
sought to (i) assess if the impact of empagliflozin … ii) determine the effect of empagliflozin on CV …

Impact of empagliflozin in patients with diabetes and heart failure

D Pham, NDA Rocha, DK McGuire… - Trends in cardiovascular …, 2017 - Elsevier
… This renal protective effect may contribute to improved heart failure outcomes as renal
impairment has been associated with worse outcomes in heart failure [35]. Moreover, potential …