Sacubitril/valsartan in heart failure: efficacy and safety in and outside clinical trials

A Abdin, M Schulz, U Riemer, B Hadëri… - … heart failure, 2022 - Wiley Online Library
Heart failure (HF) treatment has changed substantially over … Mortality and Morbidity in Heart
Failure) randomized controlled … efficacy and safety in clinical trials and daily clinical practice. …

Efficacy and safety of SGLT2 inhibitors in heart failure: systematic review and meta‐analysis

J Butler, MS Usman, MS Khan, SJ Greene… - … heart failure, 2020 - Wiley Online Library
Aims We sought to conduct a meta‐analysis regarding the safety and efficacy of sodium‐glucose
co‐transporter 2 (SGLT2) inhibitors in patients with heart failure (HF). Methods and …

Efficacy and safety of exercise training in patients with chronic heart failure: HF-ACTION randomized controlled trial

CM O'Connor, DJ Whellan, KL Lee, SJ Keteyian… - Jama, 2009 - jamanetwork.com
… young compared with the general population with heart failure and did not have heart
failure with preserved left ventricular function (or diastolic heart failure). The only measure of …

The efficacy and safety of sacubitril/valsartan in heart failure patients: a review

R Zhang, X Sun, Y Li, W He, H Zhu… - Journal of …, 2022 - journals.sagepub.com
Heart failure (HF) is one of the leading causes of morbidity and mortality worldwide.
Sacubitril/valsartan, an angiotensin receptor-neprilysin inhibitor, has been approved for the …

Clinical profiles and outcomes in patients with chronic heart failure and chronic obstructive pulmonary disease: an efficacy and safety analysis of SHIFT study

L Tavazzi, K Swedberg, M Komajda, M Böhm… - International journal of …, 2013 - Elsevier
Background Heart failure (HF) and chronic obstructive pulmonary disease (COPD) frequently
coexist, with undefined prognostic and therapeutic implications. We investigated clinical …

Efficacy and safety of tolvaptan in patients hospitalized with acute heart failure

GM Felker, RJ Mentz, RT Cole, KF Adams… - Journal of the American …, 2017 - jacc.org
… and 72 h, worsening or persistent heart failure, over-diuresis, … heart failure was defined as
the need for rescue therapy due to persistent or worsening signs and symptoms of heart failure

Efficacy and safety of spironolactone in acute heart failure: the ATHENA-HF randomized clinical trial

J Butler, KJ Anstrom, GM Felker, MM Givertz… - JAMA …, 2017 - jamanetwork.com
… worsening chronic heart failure with diabetes and/or chronic kidney disease. Eur J Heart Fail.
… or low-dose nesiritide in acute heart failure with renal dysfunction: the ROSE acute heart

Efficacy and safety of rivaroxaban in patients with heart failure and nonvalvular atrial fibrillation: insights from ROCKET AF

S van Diepen, AS Hellkamp, MR Patel… - … : Heart Failure, 2013 - Am Heart Assoc
… We explore the safety and efficacy of rivaroxaban in patients with heart failure (HF). … In this
analysis, the primary efficacy and safety treatment effects were similar between patients with …

Efficacy and safety of carvedilol in treatment of heart failure with chronic kidney disease: a meta-analysis of randomized trials

RK Wali, M Iyengar, GJ Beck, DM Chartyan… - … : Heart Failure, 2011 - Am Heart Assoc
… with concomitant heart failure and CKD is increasing. Hence, it is important to understand
whether current standard therapies have a similar degree of efficacy and safety profiles in HF …

Efficacy and safety of novel oral anticoagulants in patients with atrial fibrillation and heart failure: a meta-analysis

G Savarese, RP Giugliano, GMC Rosano… - JACC: Heart Failure, 2016 - jacc.org
… the relative efficacy and safety of … the efficacy and safety of NOACs in patients with AF and
HF enrolled in all phase III NOACs clinical trials and to detect whether the efficacy and safety of …