The extracellular matrix in ischemic and nonischemic heart failure

NG Frangogiannis - Circulation research, 2019 - Am Heart Assoc
… the matrix environment are unknown. This review article discusses the role of ECM
macromolecules in heart failure, … ), and specialized injury-associated matrix macromolecules (such …

Extracellular matrix remodeling in heart failure: a role for de novo angiotensin II generation

KT Weber - Circulation, 1997 - Am Heart Assoc
… ” in ischemic cardiomyopathy. Such an adverse accumulation of extracellular matrix initially
… mechanisms responsible for accumulation of extracellular matrix is essential to designing …

A look between the cardiomyocytes: the extracellular matrix in heart failure

EC Miner, WL Miller - Mayo Clinic Proceedings, 2006 - Elsevier
… The extracellular matrix (ECM) of the heart dynamically … With the development and progression
of heart failure, left … of heart failure and thereby its potential role as a target for therapy for …

Extracellular matrix remodeling during the progression of volume overload-induced heart failure

KR Hutchinson, JA Stewart Jr, PA Lucchesi - Journal of molecular and …, 2010 - Elsevier
… Volume overload-induced heart failure results in progressive left ventricular remodeling …
and changes in extracellular matrix (ECM) remodeling changes. The ECM matrix scaffold is an …

Extracellular matrix fibrotic markers in heart failure

F Zannad, P Rossignol, W Iraqi - Heart failure reviews, 2010 - Springer
… could prove a clinically useful tool in heart failure (HF) patients. … Extracellular matrix (ECM)
biomarkers in HF are promising biomarkers. They are able to detect early changes in heart

The dynamic extracellular matrix: intervention strategies during heart failure and atherosclerosis

S Heeneman, JP Cleutjens, BC Faber… - The Journal of …, 2003 - Wiley Online Library
heart failure. This study suggests that statin treatment might slow down the progression of
chronic heart failure. It … also retard the progression of heart failure by a beneficial modulation of …

Extracellular matrix profiles in the progression to heart failure: European Young Physiologists Symposium Keynote Lecture–Bratislava 2007

HK Graham, M Horn, AW Trafford - Acta Physiologica, 2008 - Wiley Online Library
extracellular matrix (ECM) and myocardial remodelling is a unifying feature in the progression
to heart failure… size, shape and function of the heart. It is a physiological and pathological …

Cardiac inflammation contributes to changes in the extracellular matrix in patients with heart failure and normal ejection fraction

D Westermann, D Lindner, M Kasner… - … : Heart Failure, 2011 - Am Heart Assoc
heart failure with normal ejection fraction (HFNEF) is still under discussion. Here we report
the influence of cardiac inflammation on extracellular matrix (… in the extracellular matrix (ECM). …

Extracellular matrix in heart failure: role of ADAMTS5 in proteoglycan remodeling

J Barallobre-Barreiro, T Radovits, M Fava, U Mayr… - Circulation, 2021 - Am Heart Assoc
Extracellular matrix remodeling in human heart failure. A, Histologic characterization
demonstrates diffuse fibrosis in patients with nonischemic heart failure (HF) … for extracellular and …

Cardiac extracellular matrix is associated with adverse outcome in patients with chronic heart failure

F Duca, C Zotter‐Tufaro… - … of Heart Failure, 2017 - Wiley Online Library
… the median extracellular matrix (ECM) area. (A) Entire cohort. (B) Heart failure with preserved
ejection fraction excluding patients with cardiac amyloidosis. (C) Heart failure with reduced …