[HTML][HTML] Molecular pathogenesis of myocardial remodeling and new potential therapeutic targets in chronic heart failure
G Distefano, P Sciacca - Italian journal of pediatrics, 2012 - Springer
It is well known that the natural history of chronic heart failure (CHF),regardless of age and
aetiology,is characterized by progressive cardiac dysfunction refractory to conventional …
aetiology,is characterized by progressive cardiac dysfunction refractory to conventional …
[HTML][HTML] Molecular genetics and pathogenesis of cardiomyopathy
A Kimura - Journal of human genetics, 2016 - nature.com
… HCM, a major cause of sudden death in young and heart failure, is … heart failure and often
associated with sudden death. In addition, there are other clinical types of cardiomyopathy…
associated with sudden death. In addition, there are other clinical types of cardiomyopathy…
Molecular pathogenesis and current pathology of pulmonary hypertension
VA de Jesus Perez - Heart failure reviews, 2016 - Springer
… elevated pulmonary pressures and right heart failure that predominantly affects females
of … Patients with PAH mostly present with signs of right heart failure such as fluid buildup, …
of … Patients with PAH mostly present with signs of right heart failure such as fluid buildup, …
Epigenetic mechanisms in heart failure pathogenesis
TG Di Salvo, SM Haldar - Circulation: Heart Failure, 2014 - Am Heart Assoc
… systolic heart failure (… molecular pathways underlying HF pathogenesis. Although a number
of novel myocardial signaling effectors have been implicated as drivers of HF pathogenesis, 1…
of novel myocardial signaling effectors have been implicated as drivers of HF pathogenesis, 1…
The role of inflammation and cell death in the pathogenesis, progression and treatment of heart failure
A Briasoulis, E Androulakis, T Christophides… - Heart failure …, 2016 - Springer
… , evidence is also emerging for a similar role modulated by the Ca(2+)–calmodulin-dependent
protein kinase II (CaMKII) signalling molecule in ischaemic injury and heart failure [21]. …
protein kinase II (CaMKII) signalling molecule in ischaemic injury and heart failure [21]. …
Pathogenesis and pathophysiology of heart failure with reduced ejection fraction: translation to human studies
… The Ca 2+ re-uptake channel SERCA-2a has long been implicated in the pathogenesis of
heart failure and has been the target of several clinical trials in HFrEF [34]. Normally, SERCA …
heart failure and has been the target of several clinical trials in HFrEF [34]. Normally, SERCA …
[HTML][HTML] The molecular and cellular mechanisms associated with a microvascular inflammation in the pathogenesis of heart failure with preserved ejection fraction
AG Ovchinnikov, TI Arefieva, AV Potekhina… - Acta Naturae …, 2020 - cyberleninka.ru
… Heart failure with preserved ejection fraction (HFpEF) is a … the outcome in a heart failure
with reduced ejection fraction … of these two types of heart failure and the diversity of the HFpEF …
with reduced ejection fraction … of these two types of heart failure and the diversity of the HFpEF …
[PDF][PDF] Pathophysiology of heart failure
… ABSTRACT Heart failure is considered an epidemic disease … , cellular, and molecular
mechanisms are activated and act as … determining factor in heart failure is its constant progression. …
mechanisms are activated and act as … determining factor in heart failure is its constant progression. …
[HTML][HTML] Reactive oxygen species induced pathways in heart failure pathogenesis and potential therapeutic strategies
A Mongirdienė, L Skrodenis, L Varoneckaitė… - Biomedicines, 2022 - mdpi.com
… With respect to structural and functional cardiac disorders, chronic heart failure (CHF) is
classified into heart failure (HF) with reduced ejection fraction (HFrEF) and HF with preserved …
classified into heart failure (HF) with reduced ejection fraction (HFrEF) and HF with preserved …
[HTML][HTML] The critical roles of protein quality control systems in the pathogenesis of heart failure
Y Maejima - Journal of Cardiology, 2020 - Elsevier
… heart failure, including drug therapies, device therapies, and regeneration therapies. However,
as each of these heart failure … therapeutic strategies for heart failure in a fundamental way…
as each of these heart failure … therapeutic strategies for heart failure in a fundamental way…
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