… Changes occurring in the cellular constituents of the myocardium that accompany … the
myocardial interstitium will be the focus of this article. Historically, the myocardial interstitium was …

… Myocardial fibrosis and interstitial heart disease occur when collagen homeostasis becomes
dysregulated and excess collagen accumulates in the interstitium secreted by activated …

… of identifying the cause of interstitial expansion in heart failure patients resulting from the …
of many different myocardial diseases, routine assessment of the interstitium via advanced …

… with severe aortic stenosis and heart failure showing myocardial interstitial fibrosis. Sections
… ), and large strands diffusely localized across the interstitium (c) and around intramyocardial …

… Interstitial heart disease, whether primarily from myocardial fibrosis or cardiac amyloidosis,
… accumulation in the interstitium and constitutes a major source of heart failure with excess …

… resonance may detect underlying myocardial disease, endocardial disease, or … interstitial
expansion seen in diffuse myocardial fibrosis, which is usually less than the extreme interstitial …

… The induction of MMPs within the myocardium during the heart failure process probably …
myocardial interstitium and, in turn, prove to be a useful therapeutic paradigm for heart failure …

… chronic heart failure showed considerable degenerative changes of constituent myocytes
of myocardial regions that manifested severe interstitial fibrosis compared to constituent …

… ventricular (LV) stiffness in patients with heart failure (HF),4,5 … estimate the extent of
myocardial interstitial fibrosis in order … eter and extent of myocardial interstitial fibrosis, which was …

… Chronic treatment with torasemide (TX) in heart failure patients on top of standard therapy
reduced myocardial interstitial fibrosis (panel A); collagen cross-linking (panel B); active LOX …