Bioactive peptide signaling within the myocardial interstitium and the matrix metalloproteinases

FG Spinale - Circulation research, 2002 - Am Heart Assoc
… in end-stage heart failure and in nonfailing … myocardium, a robust increase was detected
in heart failure samples. Thus, MT1-MMP, which is constitutively active within the myocardial

Pericardial and pleural effusions in congestive heart failure—anatomical, pathophysiologic, and clinical considerations

A Natanzon, I Kronzon - The American journal of the medical sciences, 2009 - Elsevier
… differences between vascular, interstitial, and lymphatic beds within the heart result in a net
… into the myocardial interstitial space, and, ultimately, into the myocardial lymphatic system. …

Evolving changes in lung interstitial fluid content after acute myocardial infarction: mechanisms and pathophysiological correlates

M Guazzi, R Arena, MD Guazzi - … of Physiology-Heart and …, 2008 - journals.physiology.org
… In acute myocardial infarction (AMI), alveolar interstitium … microvascular endothelium, eliciting
interstitial overflow and altering … with congestive heart failure complicating acute myocardial

[HTML][HTML] Correlation of myocardial interstitial collagen in the right ventricular septum with ventricular function of patients with ischemic cardiomyopathy

MW Montera, C Drumond, C Takiya… - Arquivos Brasileiros …, 2009 - SciELO Brasil
… Yet, only in explanted hearts with end-stage heart failure would such analysis be possible,
and this was beyond the scope of this study. Another limiting factor was the lack of a control …

Myocyte loss in chronic heart failure

NB Rayment, AJ Haven, B Madden… - The Journal of …, 1999 - Wiley Online Library
Interstitial macrophages and T cells and their relationship to myocyte loss were also examined.
… Evidence of cardiocyte apoptosis in myocardium of dogs with chronic heart failure. Am J …

Active interstitial remodeling: an important process in the hibernating human myocardium

NG Frangogiannis, S Shimoni, SM Chang… - Journal of the American …, 2002 - jacc.org
Objectives : The purpose of this study is to investigate the morphologic characteristics of the
cardiac interstitium in the hibernating human myocardium and evaluate whether active …

Evaluation of Diffuse Myocardial Fibrosis in Heart Failure With Cardiac Magnetic Resonance Contrast-Enhanced T1 Mapping

L Iles, H Pfluger, A Phrommintikul, J Cherayath… - Journal of the American …, 2008 - jacc.org
… Post-contrast myocardial T 1 times correlated histologically with … heart failure subjects than
controls (383 ± 17 ms vs. 564 ± 23 ms, p < 0.0001). The T 1 time of heart failure myocardium

… by extracellular volume is associated with subsequent hospitalization for heart failure, death, or both across the spectrum of ejection fraction and heart failure stage

EB Schelbert, KM Piehler, KM Zareba… - … of the American Heart …, 2015 - Am Heart Assoc
myocardial infarction [MI] is present) may be an identifiable and potentially treatable interstitial
… vulnerability to adverse outcomes including hospitalization for heart failure (HHF), death, …

Pathophysiology of the Lymphatic System in Patients With Heart Failure: JACC State-of-the-Art Review

M Itkin, SG Rockson, D Burkhoff - Journal of the American College of …, 2021 - jacc.org
interstitial space, and the role of the lymphatic system in maintaining fluid homeostasis within
the interstitium have received little attention in heart failuremyocardial interstitium: effects of …

Pathologic hypertrophy with fibrosis: the structural basis for myocardial failure

KT Weber, CG Brilla, SE Campbell, G Zhou… - Blood …, 1992 - Taylor & Francis
… in myocardial mass associated with such growth that are responsible for the increased risk
of heart failure, sudden death and myocardial … The perivascular/ interstitial fibrous tissue …