… To the best of our knowledge, this is the first study using a plasma proteomic approach (2D
LC ESI-MS/MS in HDMSE) to increase the understanding about the pathogenesis of HF and …

… Heart failure (HF) is a major public health problem characterized by inability of the heart to
… Here we report application of aptamer-based proteomics to identify proteins associated with …

… In this study, we focused on the plasma proteome’s association with overall survival in patients
with HFrEF and took a staged (derivation and separate validation) approach, successfully …

… First, the large scale of the plasma proteomic array and whole-genome approach of the …
plasma proteome have found typically intracellular proteins to be associated with cardiovascular …

… methods, complicating the validation process for novel protein biomarkers. Typically, MS
method … abundant proteins such as albumin in plasma samples, further separation of each …

… Underlying mechanisms in heart failure (HF) with preserved ejection fraction remain unknown.
We investigated cardiovascular plasma biomarkers in HF with preserved ejection fraction …

… Using this method, we observed the effect of HF stage on proteome (by comparing between
… had access to plasma samples for the patients with stage C, we chose to use plasma for the …

… cardiac biomarker discovery and validation by proteomic analysis of cardiac myocytes/ tissue
or serum/plasma… to completely characterize the proteome, new methods and strategies are …

… plasma proteome of AMI patients who had and did not have HF in order to provide insights
into the pathogenesis of disease … mechanisms involved by investigating the plasma proteome. …

… the body in health and disease. Even if efforts have been always dedicated to the refinement
of proteomic approaches to investigate more deeply the plasma proteome, it should not be …