Plasma proteomic profile predicts survival in heart failure with reduced ejection fraction

H Gui, R She, J Luzum, J Li, TD Bryson… - Circulation: Genomic …, 2021 - Am Heart Assoc
… whether the plasma proteome adds value to established predictors in heart failure (HF) with
reduced ejection fraction (HFrEF). We sought to derive and validate a plasma proteomic risk …

Plasma proteomic approach in patients with heart failure: insights into pathogenesis of disease progression and potential novel treatment targets

TH Cao, DJL Jones, AA Voors, PA Quinn… - … of heart failure, 2020 - Wiley Online Library
… The results in this study showed that plasma proteomics provides insights into the
pathogenesis of disease progression in HF that would open new perspectives for translational …

Identifying plasma proteomic signatures from health to heart failure, across the ejection fraction spectrum

K Andrzejczyk, S Abou Kamar, AM van Ommen… - Scientific Reports, 2024 - nature.com
heart failure (HF) with preserved ejection fraction (HFpEF) and reduced ejection fraction (HFrEF)…
We aimed to identify specific proteomic patterns for HF, by comparing proteomic profiles

Proteomic bioprofiles and mechanistic pathways of progression to heart failure: the HOMAGE study

JP Ferreira, J Verdonschot, T Collier… - … : Heart Failure, 2019 - Am Heart Assoc
… The intracellular transcription factors TP53, HNF1B, HIF1A/ARNT, and STAT6, which are
not measured in our plasma protein panels, may complement the biomarker profile of patients …

Circulating proteomic signature of early death in heart failure patients with reduced ejection fraction

M Cuvelliez, V Vandewalle, M Brunin, O Beseme… - Scientific reports, 2019 - nature.com
proteomic profiling platform. In total, 203 proteins were significantly modulated in the plasma
… 1, we then used 2 strategies for analysing our high-throughput proteomic profiles. First, we …

Plasma protein profile of incident myocardial infarction, ischemic stroke, and heart failure in 2 cohorts

L Lind, J Ärnlöv, J Sundström - Journal of the American Heart …, 2021 - Am Heart Assoc
… Of those, we have proteomic data in 761 individuals. A total of 166 subjects were
excluded from the analyses due to prevalent CVD at the baseline examination at age 77. …

Plasma Olink Proteomics Reveals Novel Biomarkers for Prediction and Diagnosis in Dilated Cardiomyopathy with Heart Failure

S Xu, G Zhang, X Tan, Y Zeng, H Jiang… - Journal of Proteome …, 2024 - ACS Publications
… with dilated cardiomyopathy combined with heart failure (DCM-HF), providing comprehensive
proteomic insights. … Landscape of plasma proteins profile. (A) Heatmap of all expressed …

[HTML][HTML] Plasma proteomic analysis of association between atrial fibrillation, coronary microvascular disease and heart failure

G Dixit, J Blair, C Ozcan - … Journal of Cardiovascular Disease, 2022 - ncbi.nlm.nih.gov
… We hypothesized that plasma proteomic analysis can identify … -free quantitative proteomics
approach was used in plasma … In conclusion, plasma proteomic profile provides biomarkers …

Multimarker proteomic profiling for the prediction of cardiovascular mortality in patients with chronic heart failure

G Lemesle, F Maury, O Beseme, L Ovart, P Amouyel… - PLoS …, 2015 - journals.plos.org
Proteomics has been used to provide prognostic information in various diseases. Our aim
… value of plasma proteomic profiling for risk stratification in HF. A proteomic profiling using …

Prevalence, risk factors and proteomic bioprofiles associated with heart failure in rheumatoid arthritis: The RA-HF study

MB Ferreira, T Fonseca, R Costa, A Marinhoc… - European Journal of …, 2021 - Elsevier
… Patients with rheumatoid arthritis and heart failure largely share similar mechanistic
pathways with patients with heart failure without rheumatoid arthritis. These include a higher …