Reverse remodeling in heart failure—mechanisms and therapeutic opportunities

N Koitabashi, DA Kass - Nature Reviews Cardiology, 2012 - nature.com
… Here, we review the current evidence for reverse remodeling by … reverse remodeling by
existing therapies, and provide an outlook on promising novel approaches to reverse remodeling

Reverse remodeling in heart failure–fact or fiction?

B Pieske - European Heart Journal Supplements, 2004 - academic.oup.com
… of development and progression of heart failure, and how therapy … Remodeling and reverse
remodeling The progression of heart failure is associated with left ventricular remodeling, …

Reverse remodeling in systolic heart failure

T Saraon, SD Katz - Cardiology in review, 2015 - journals.lww.com
… the LV remodeling process. In this article, we review selected studies that demonstrate the
LV reverse remodeling … to effect reverse remodeling may further improve clinical outcomes in …

[HTML][HTML] Left ventricular reverse remodeling in heart failure: remission to recovery

J Boulet, MR Mehra - Structural Heart, 2021 - Elsevier
… and reverse remodeling are complex and differ in many ways from remodeling processes …
Similarly, we shall not discuss the syndrome of heart failure with preserved ejection fraction …

Reversing chronic remodeling in heart failure

JO Mudd, DA Kass - Expert review of cardiovascular therapy, 2007 - Taylor & Francis
… For the purpose of this review, we use the original definition of reverse remodeling – that is,
a process where failing hearts can now function at smaller chamber volumes (particularly end…

[HTML][HTML] Redefining reverse remodeling: can echocardiography refine our ability to assess response to heart failure treatments?

AA Waring, SE Litwin - Journal of the American College of Cardiology, 2016 - jacc.org
… pathological remodeling. Similar changes in LV geometry have been observed in patients
with nonischemic causes of heart failure (HF) (5). The concept of reverse remodeling was …

Biomarkers to predict reverse remodeling and myocardial recovery in heart failure

SR Motiwala, HK Gaggin - Current heart failure reports, 2016 - Springer
… of assessing remodeling and reverse remodeling is that they … the underlying biology of
remodeling or reverse remodeling. It … pathways of remodeling or reverse remodeling earlier in the …

Reverse remodeling and enhancedadrenergic reserve from passive externalsupport in experimental dilated heart failure

WF Saavedra, RS Tunin, N Paolocci, T Mishima… - Journal of the American …, 2002 - jacc.org
Objectives : We sought to test the efficacy of a passive elastic containment device to reverse
chronic chamber remodeling and adrenergic down-regulation in the failing heart, yet still …

Reverse cardiac remodeling and ARNI therapy

A Abboud, JL Januzzi - Current heart failure reports, 2021 - Springer
… As the central process in heart failure, remodeling serves as a pivotal point upon which … of
heart failure with reduced ejection fraction (HFrEF) prominently includes adverse remodeling

Myocardial reverse remodeling

JL Hellawell, KB Margulies - Cardiovascular therapeutics, 2012 - Wiley Online Library
… to chamber volume, and other shape changes that can affect pump function, energy utilization,
and the risk of unfavorable clinical sequelae including valvular dysfunction, heart failure (…