Endothelial dysfunction in heart failure: mechanisms and therapeutic approaches
J Bauersachs, A Schafer - Current vascular pharmacology, 2004 - ingentaconnect.com
… heart failure (CHF… failure, a reduction of endothelial NO release was associated with an
attenuated expression of eNOS [13, 14]. Data on basal production of NO in ischemic heart failure …
attenuated expression of eNOS [13, 14]. Data on basal production of NO in ischemic heart failure …
Therapeutic approaches in heart failure with preserved ejection fraction: past, present, and future
J Wintrich, I Kindermann, C Ukena, S Selejan… - Clinical Research in …, 2020 - Springer
… therapies for heart failure with reduced ejection fraction (HFrEF), therapeutic efforts in the past
have failed … This review highlights the past, present, and future therapeutic approaches in …
have failed … This review highlights the past, present, and future therapeutic approaches in …
Ca2+ Cycling and New Therapeutic Approaches for Heart Failure
AM Lompré, RJ Hajjar, SE Harding, EG Kranias… - Circulation, 2010 - Am Heart Assoc
Heart failure (HF) is a major health problem in Western countries. Despite significant progress
in pharmacological and device-based treatment, the disease burden imposed continues …
in pharmacological and device-based treatment, the disease burden imposed continues …
Contemporary approach to treating heart failure
A Brann, H Tran, B Greenberg - Trends in Cardiovascular Medicine, 2020 - Elsevier
… Over the past several decades, important advances have been made in the treatment of
patients with heart failure (HF). Whereas in the past, the main goal of drug therapy was to relieve …
patients with heart failure (HF). Whereas in the past, the main goal of drug therapy was to relieve …
Pathophysiology and therapeutic approaches to acute decompensated heart failure
JN Njoroge, JR Teerlink - Circulation research, 2021 - Am Heart Assoc
… decompensated heart failure (ADHF) is one of the leading admission diagnoses worldwide,
yet it is an entity with incompletely understood pathophysiology and limited therapeutic …
yet it is an entity with incompletely understood pathophysiology and limited therapeutic …
[PDF][PDF] The role of inflammation in heart failure: new therapeutic approaches
… in order to investigate the role of inflammation and to seek possible therapeutic approaches.
… systolic heart failure (Hellenic Heart Failure Study). Heart Vessels. 2009; 24: 22-26. 39. …
… systolic heart failure (Hellenic Heart Failure Study). Heart Vessels. 2009; 24: 22-26. 39. …
The burden of iron deficiency in heart failure: therapeutic approach
BML Rocha, GJL Cunha, LF Menezes Falcao - Journal of the American …, 2018 - jacc.org
Heart failure (HF) is highlighted by its burdening symptom-limited exercise capacity and
recurrent hospitalizations. Despite substantial advances regarding disease-modifying drugs in …
recurrent hospitalizations. Despite substantial advances regarding disease-modifying drugs in …
Targeting NOS as a therapeutic approach for heart failure
… cardiac disease conditions, such as heart failure, contributing to the contractile dysfunction,
… and potential therapeutic approaches targeting nitric oxide signaling to treat heart disease. …
… and potential therapeutic approaches targeting nitric oxide signaling to treat heart disease. …
Anemia and iron deficiency in heart failure: mechanisms and therapeutic approaches
DJ Van Veldhuisen, SD Anker, P Ponikowski… - Nature Reviews …, 2011 - nature.com
Anemia and iron deficiency are common in patients with heart failure (HF), and are associated
with worse symptoms and adverse outcomes in this population. Although the two can …
with worse symptoms and adverse outcomes in this population. Although the two can …
Novel therapeutic approaches for heart failure by normalizing calcium cycling
XHT Wehrens, AR Marks - Nature Reviews Drug Discovery, 2004 - nature.com
… Congestive heart failure is the leading cause of death in the Western world. Abnormal
intracellular calcium (Ca 2+ ) handling is central to the pathogenesis of heart failure because it …
intracellular calcium (Ca 2+ ) handling is central to the pathogenesis of heart failure because it …
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