The natriuretic peptides in heart failure: diagnostic and therapeutic potentials

HH Chen, JC Burnett Jr - Proceedings of the Association of …, 1999 - Wiley Online Library
… Congestive heart failure (CHF) represents a pathological state in … heart failure, the diagnostic
and prognostic significance of the natriuretic peptides in CHF, and the therapeutic potential

The apelin–APJ system in heart failure: pathophysiologic relevance and therapeutic potential

AG Japp, DE Newby - Biochemical pharmacology, 2008 - Elsevier
… –APJ regulation in the setting of heart failure and consider how attenuated apelin signalling
… will explore the therapeutic potential of targeting the apelin–APJ system in heart failure and, …

Therapeutic potential for HDAC inhibitors in the heart

TA McKinsey - Annual review of pharmacology and toxicology, 2012 - annualreviews.org
… to be efficacious in preclinical models of heart failure. This review highlights roles of HDACs
in the heart and the therapeutic potential of HDAC inhibitors for the treatment of heart failure. …

[HTML][HTML] Natriuretic peptides: physiology, therapeutic potential, and risk stratification in ischemic heart disease

BC Stein, RI Levin - American heart journal, 1998 - Elsevier
… They are similarly upregulated in heart failure and counteract neurohormones that
induce vasoconstriction and fluid retention. BNP may be the superior prognosticator for risk …

β-Adrenoceptor antagonists in elderly patients with chronic heart failure: therapeutic potential of third-generation agents

AJS Coats - Drugs & aging, 2006 - Springer
… placebo-controlled trial of carvedilol in addition to standard heart failure therapy in 2289
patients with moderate to severe heart failure who were clinically euvolaemic and had an EF of <…

New therapeutic options in congestive heart failure: part I

J McMurray, MA Pfeffer - Circulation, 2002 - Am Heart Assoc
… With the combination of heart failure and myocardial infarction in post–myocardial infarction
studies collectively, we can now feel comfortable with the fact that the combination therapy is …

Therapeutic targets in heart failure: refocusing on the myocardial interstitium

EB Schelbert, GC Fonarow, RO Bonow, J Butler… - Journal of the American …, 2014 - jacc.org
… New therapeutic targets, agents, and strategies are needed to prevent and treat heart
failure (HF) after a decade of failed research efforts to improve long-term patient outcomes, …

Inflammatory and anti‐inflammatory cytokines in chronic heart failure: potential therapeutic implications

P Aukrust, L Gullestad, T Ueland, JK Damås… - Annals of …, 2005 - Taylor & Francis
… play a pathogenic role in chronic heart failure (HF) by influencing heart contractility, inducing
… Thus, these cytokines could have a therapeutic potential as adjuvants in stem cell therapy. …

Molecular pathogenesis of myocardial remodeling and new potential therapeutic targets in chronic heart failure

G Distefano, P Sciacca - Italian journal of pediatrics, 2012 - Springer
… It is well known that the natural history of chronic heart failure (CHF),regardless of age and
… cardiokinetic, diuretic and peripheral vasodilator therapy. Several previous studies, both in …

Implications of the natriuretic peptide system in the pathogenesis of heart failure: diagnostic and therapeutic importance

Z Abassi, T Karram, S Ellaham, J Winaver… - … & therapeutics, 2004 - Elsevier
… be increased in patients with various heart diseases, the elevation in circulatory … heart failure
in patients admitted to the emergency room with symptoms of decompensated heart failure. …