Disrupted serotonergic and sympathoadrenal systems in patients with chronic heart failure may serve as new therapeutic targets and novel biomarkers to assess …
RR Nigmatullina, VV Kirillova, RK Jourjikiya… - Cardiology, 2009 - karger.com
… of heart failure progression has recently become universally recognized. According to this
tenet, heart failure … diagnostic approaches and at the same time serve as therapeutic targets. …
tenet, heart failure … diagnostic approaches and at the same time serve as therapeutic targets. …
Endoplasmic reticulum stress as a novel therapeutic target in heart diseases
A Toth, P Nickson, A Mandl… - … -Drug Targets …, 2007 - ingentaconnect.com
… Puma, therefore, represents a potential therapeutic target to attenuate cell death in a variety
of different conditions, including ischemic heart disease, heart failure or during cell therapy …
of different conditions, including ischemic heart disease, heart failure or during cell therapy …
Disease pathways and novel therapeutic targets in hypertrophic cardiomyopathy
H Ashrafian, WJ McKenna, H Watkins - Circulation research, 2011 - Am Heart Assoc
… Therapeutic targets in HCM are likely to be most effective when directed to the molecular …
heart failure and hypertrophic cardiomyopathy and for its use in systolic heart failure in …
heart failure and hypertrophic cardiomyopathy and for its use in systolic heart failure in …
miRNAs as therapeutic targets in ischemic heart disease
RJA Frost, E van Rooij - Journal of cardiovascular translational research, 2010 - Springer
… Ischemic heart disease is a form of congestive heart failure that is caused by insufficient …
therapeutic target for cardiac remodeling is miR-208. miR-208 is solely expressed in the heart as …
therapeutic target for cardiac remodeling is miR-208. miR-208 is solely expressed in the heart as …
Myocardial matrix degradation and metalloproteinase activation in the failing heart: a potential therapeutic target
FG Spinale, ML Coker, BR Bond… - Cardiovascular …, 2000 - academic.oup.com
… Regulation of myocardial MMP expression and activity may be an important therapeutic
target for controlling myocardial matrix remodeling in the setting of developing heart failure. …
target for controlling myocardial matrix remodeling in the setting of developing heart failure. …
Signaling cascades in the failing heart and emerging therapeutic strategies
X He, T Du, T Long, X Liao, Y Dong… - … and targeted therapy, 2022 - nature.com
… heart failure is the end stage of cardiac diseases. With a high prevalence and a high mortality
rate worldwide, chronic heart failure … novel insights for future therapeutic targets. On the …
rate worldwide, chronic heart failure … novel insights for future therapeutic targets. On the …
Pak1 as a novel therapeutic target for antihypertrophic treatment in the heart
W Liu, M Zi, R Naumann, S Ulm, J Jin, DM Taglieri… - Circulation, 2011 - Am Heart Assoc
… to heart failure, we extended the TAC stress imposed on Pak1 f/f and Pak1 cko mice to 5
weeks. Indeed, Pak1 cko mice showed characteristics of heart failure … confirmed heart failure, …
weeks. Indeed, Pak1 cko mice showed characteristics of heart failure … confirmed heart failure, …
miRNAS in cardiovascular diseases: potential biomarkers, therapeutic targets and challenges
S Zhou, J Jin, J Wang, Z Zhang, JH Freedman… - Acta Pharmacologica …, 2018 - nature.com
… therapeutic targets for several cardiovascular disorders. In this review we provides an overview
of the effects of several CVD; including heart failure, … miRNA as therapeutic targets is also …
of the effects of several CVD; including heart failure, … miRNA as therapeutic targets is also …
MicroRNAs in heart failure: from biomarker to target for therapy
EL Vegter, P van der Meer, LJ de Windt… - … of heart failure, 2016 - Wiley Online Library
… to therapy. Several miRNAs have been related to important mechanisms leading to heart
failure… An increasing number of miRNAs and miRNA targets have been reported in heart failure …
failure… An increasing number of miRNAs and miRNA targets have been reported in heart failure …
Heart rate variability–a therapeutic target?
HC Routledge, S Chowdhary… - … and therapeutics, 2002 - Wiley Online Library
… with moderate or severe heart failure, those with depressed … of death due to progressive heart
failure than conventional clinical … to high risk patients with heart failure or MI. Low HRV has …
failure than conventional clinical … to high risk patients with heart failure or MI. Low HRV has …