… work induced by the sudden increase in perfusion pressure on the rates of tricarboxylatecycle …
effects of cardiac work on cycle turnover to be compared at very different concentrations of …

… 47 NELLY, JR, DENTON, RM, ENGLAND, PJ, RANDLE, PJ The effects of increased heart
work on the tricarboxylate cycle and its interactions with glycolysis in the perfused rat heart. …

… in the heart. Glutamine and asparagine did not appear to contribute carbon to the tricarboxylate
cycle. Thus the concentration of glutamine was 3.6,umol/g dry wt. of heart at the …

… In the present study, glutamate and aspartate pool sizes were calculated from the '3C NMR
data for each heart, and citric acid cycle intermediate pool sizes too small to be quantified by `…

… NEELY, JR, DENTON, RM, ENGLAND, PJ & RANDLE, PJ The effects of increased heart
work on the tricarboxylate cycle and its interactions with glycolysis in the perfused rat heart. …

… absolute activities are somewhat higher in the present work. The lesser loss of activity of" 2-…
for the tricarboxylate cycle. In the heart, the decrement in tricarboxylate cycle enzyme activity …

… of TCA cycle intermediates and can potentially participate in cycle anaplerosis … The importance
of aspartate in the operation of the TCA cycle in heart muscle … Control of the tricarboxylate …

… cardiac TCA cycle activity. The purpose of the current work was to test the hypothesis that
"C NMR parameters alone can be used to index TCA cycle flux noninvasively in intact hearts. …

… Relative inhibition of the citric acid cycle in rat heart perfused with ketone bodies (acetoacetate
or ~-hydroxybutyrate) as the only exogenous substrate. Comparison of glucose and …

… ) cycle intermediates (TCAI) and the control of cycle activity have been characterized in the
isolated, perfused rat heart (… Flux through the TCA cycle is believed to be primarily regulated …