… in the presence of carnitine or high concentrations of proline, or on lengthy incubation in
the presence of either of the systems used to generate intramitochondrial tricarboxylate-cycle …

… Calcium, a major intracellular metabolic signal, is reversibly sequestered by mitochondria,
playing a role in stimulation of the tricarboxylate cycle in the mitochondrial matrix. In heart, the …

… current work, we have utilized isolated cardiomyocytes to assess the influence of HzOz-induced
oxidative stress on heart muscle TCA cycle … The lack of a tricarboxylate carrier in cardiac …

… In conclusion, rat heart has the capability to chain-elongate fatty acids using mitochondria-derived
two-carbon chain extenders. The data suggest that the chain elongation process is …

… This is not a moot issue in the case of the isolated working rat heart, because we … heart
work on the tricarboxylate cycle and its interactions with glycolysis in the perfused rat heart…

… model that includes key, rate-limiting tricarboxylate pools as well as the major contributing
… flux in heartsat normal workload and was twice the TCA cycle flux in KCl-arrested hearts. …

… spectrum of dicarboxylates and tricarboxylates, it has been … into the tricarboxylic acid cycle
to support ATP synthesis and the … tricarboxylate carrier is high in liver compared to that in heart …

… Recent work from this laboratory has shown that the transport of phosphoenolpyruvate in
mitochondria from rat liver, guinea-pig liver and rat heart can be mediated by the tricarboxylate …

… interactions in the control of citric acid cycle activity in rat heart mitochondria. J Biol Chem …
heart work on the tricarboxylate cycle and its interactions with glycolysis in perfused rat heart…

… due to the apparent low activity of the tricarboxylate carrier [31]in heart mitochondria. …
hearts is not a change in TCA cycle activity, but rather the source of acetyl CoA for the TCA cycle. …