[5-3H]glucose overestimates glycolytic flux in isolated working rat heart: role of the pentose phosphate pathway

GW Goodwin, DM Cohen… - American Journal of …, 2001 - journals.physiology.org
… This is not a moot issue in the case of the isolated working rat heart, because we … heart
work on the tricarboxylate cycle and its interactions with glycolysis in the perfused rat heart

Compartmentation of Citrate in Heart and Adipose Tissue

RM Denton - Metabolic Compartmentation in the Brain: Proceedings …, 1973 - Springer
… of the tricarboxylic acid cycle following onset of acetate oxidation in rat heart. Some of the …
In liver mitochondria it has been proposed that there are: a tricarboxylate carrier catalysing …

Functional coupling as a basic mechanism of feedback regulation of cardiac energy metabolism

VA Saks, AV Kuznetsov, M Vendelin… - Molecular and cellular …, 2004 - Springer
… Neely JR, Denton RM, England PJ, Randle PJ: The effects of increased heart work on the
tricarboxylate cycle and its interactions with glycolysis in the perfused rat heart. Biochem J 128: …

Regulation of energy substrate metabolism in the diabetic heart

WC Stanley, GD Lopaschuk… - Cardiovascular …, 1997 - academic.oup.com
… due to the apparent low activity of the tricarboxylate carrier [31]in heart mitochondria. …
hearts is not a change in TCA cycle activity, but rather the source of acetyl CoA for the TCA cycle. …

Demonstration of physical interactions between consecutive enzymes of the citric acid cycle and of the aspartate‐malate shuttle: a study involving fumarase, malate …

S Beeckmans, L Kanarek - European journal of biochemistry, 1981 - Wiley Online Library
… in vitro (ATP, pyridine nucleotides and tricarboxylate compounds) have been proven to be …
enzyme from pig heart in the interaction with pig heart mitochondrial malate dehydrogenase [7]…

A simulation study on the constancy of cardiac energy metabolites during workload transition

R Saito, A Takeuchi, Y Himeno… - The Journal of …, 2016 - Wiley Online Library
heart is a continuously working pump that is energetically driven by hydrolysis of ATP. In the
heart… because all of the components of the citric acid cycle, and PDHC, are activated by the …

Substrate selection in the isolated working rat heart: effects of reperfusion, afterload, and concentration

FMH Jeffrey, V Diczku, AD Sherry… - Basic research in …, 1995 - Springer
… Randle PJ, England PJ, Denton RM (1970) Control of the tricarboxylate cycle and its
interactions with glycolysis during acetate utilization in rat heart. Biochem J 117:677-95 32. Regan …

Production and export of metabolites from liver and heart mitochondria and anaplerosis

MJ MacDonald - Molecular and cellular biochemistry, 2004 - Springer
… the citric acid cycle some cycle intermediates are synthesized … Theoretically, synthesis of
cycle intermediates should be … with citrate on the mitochondrial tricarboxylate transporter. In liver …

Metabolic heterogeneity of carbon substrate utilization in mammalian heart: NMR determinations of mitochondrial versus cytosolic compartmentation

ED Lewandowski - Biochemistry, 1992 - ACS Publications
… the tricarboxylate pool of the … hearts to be influenced by the balance between TCA cycle
intermediate oxidation and interconversion with thetissue glutamate pool. Thus, the current work

Regulation of fatty acid oxidation in heart

H Schulz - The Journal of nutrition, 1994 - Elsevier
… The perfused working heart has been used to study how the concentration of free fatty acids
in the per… isocitrate during tricarboxylate cycle oxidations in rabbit heart mitochondria. J. Biol. …