Heat stroke and cytokines

LR Leon - Progress in brain research, 2007 - Elsevier
heat load to the body, has likely increased heat stroke … (1946) proposed direct thermal
injury to the thermoregulatory … of heat stroke mortality, despite an inability to detect thermal

Use of the heat tolerance test to assess recovery from exertional heat stroke

KM Mitchell, SN Cheuvront, MA King, TA Mayer… - Temperature, 2019 - Taylor & Francis
… High air temperatures, solar loads, and absolute humidity combined with low air flows and …
that the determination of heat intolerance should be based upon the thermal-circulatory ratio (…

Unique cytokine and chemokine responses to exertional heat stroke in mice

MA King, LR Leon, DA Morse… - Journal of Applied …, 2017 - journals.physiology.org
… reflect differences in the overall thermal load between PHS and EHS. … thermal area was
matched, using an elevated T env in the chamber (43.5C). This resulted in an average thermal

Classic and exertional heatstroke

A Bouchama, B Abuyassin, C Lehe, O Laitano… - Nature Reviews …, 2022 - nature.com
… In the past two decades, record-breaking heatwaves have caused an increasing number of
heat-related deaths, including heatstroke, globally. Heatstroke is a heat illness characterized …

Controversies in exertional heat stroke diagnosis, prevention, and treatment

O Laitano, LR Leon, WO Roberts… - Journal of Applied …, 2019 - journals.physiology.org
… 47) reported improved thermal tolerance in monkeys passively exposed to heat stress when
… fever would add to the overall heat load and reduced heat tolerance. More important is the …

The thermoregulatory consequences of heat stroke: are cytokines involved?

LR Leon - Journal of Thermal Biology, 2006 - Elsevier
… from heat cramps, to heat exhaustion and ultimately heat stroke, … c ) values associated with
heat exhaustion and heat stroke, despite … used to induce a thermal load (eg, heat shock vs. …

Sex-dependent responses to exertional heat stroke in mice

CK Garcia, AJ Mattingly, GP Robinson… - Journal of Applied …, 2018 - journals.physiology.org
heat injury or heat stroke. In this study we compared responses of male and female adult
mice to exertional heat stroke (… Ascending thermal area was used as an index of thermal load

Prior viral illness increases heat stroke severity in mice

SM Dineen, JA Ward, LR Leon - Experimental Physiology, 2021 - Wiley Online Library
… To address this issue, we used an established mouse model of heat stroke to determine the
Thermal load (in degrees Celsius multiplied by minutes; measured as thermal area) was …

Exertional heat stroke in sport and the military: epidemiology and mitigation

JD Périard, D DeGroot, O Jay - Experimental physiology, 2022 - Wiley Online Library
… In military environments, heat illness risk is often exacerbated by heavy carrying loads, …
conditions – the NRL heat policy was updated to account for the thermal characteristics of the …

Biochemical recovery from exertional heat stroke follows a 16-day time course

MD Ward, MA King, C Gabrial, RW Kenefick, LR Leon - PLoS One, 2020 - journals.plos.org
… with the thermal load, a function of the degree and duration of hyperthermia [17,18]. … Over
the study period, we recorded 2,216 patients experiencing a total of 2,529 heat stroke episodes …