Recombinant human stem cell factor, a c-kit ligand, stimulates hematopoiesis in primates

RG Andrews, GH Knitter, SH Bartelmez, KE Langley… - 1991 - ashpublications.org
… soluble SCF on hematopoiesis both in vitro and in vivo in nonhuman primates. We found
that in vitro SCF enhanced the growth of both myeloid and erythroid colony-forming cells, and …

Stem cell factor and hematopoiesis

VC Broudy - Blood, The Journal of the American Society of …, 1997 - ashpublications.org
… Injection of mice with SCF results in a profound redistribution of primitive hematopoietic
cells from the bone marrow into the blood and spleen.195,196 Primates treated with SCF …

Recombinant human megakaryocyte growth and development factor stimulates thrombocytopoiesis in normal nonhuman primates

AM Farese, P Hunt, T Boone, TJ MacVittie - 1995 - ashpublications.org
… with variable responses in the frequency of hematopoietic progenitor cells (HPC). Such
variability in the platelet response from primate preclinical studies predicted similar responses in …

… development factor, and interleukin-3 in combination soon after irradiation prevents nonhuman primates from myelosuppression: long-term follow-up of hematopoiesis

M Drouet, F Mourcin, N Grenier, V Leroux, J Denis… - Blood, 2004 - ashpublications.org
… Preservation of hematopoietic stem and progenitor cell survival is required for recovery from
… the hematopoietic response of cynomolgus monkeys to a single dose of stem cell factor, FLT…

Development of primitive and definitive hematopoiesis from nonhuman primate embryonic stem cells in vitro

K Umeda, T Heike, M Yoshimoto, M Shiota, H Suemori… - 2004 - journals.biologists.com
hematopoiesis can be induced from primate ES cells by co-culture with OP9 stromal cells.
This … regulating primate hematopoietic development and differentiation during embryogenesis. …

Stem cell factor

IK McNiece, RA Briddell - Journal of leukocyte biology, 1995 - Wiley Online Library
… Stem cell factor (SCF) is the ligand for the tyrosine kinase … hematopoietic progenitor cells.
In vitro, SCF synergizes with other growth factors, such as granulocyte colony‐stimulating factor

Recombinant human granulocyte colony-stimulating factor. Effects on hematopoiesis in normal and cyclophosphamide-treated primates.

K Welte, MA Bonilla, AP Gillio, TC Boone… - The Journal of …, 1987 - rupress.org
… human granulocyte colonystimulating factor (rhG-CSF) in primates (cynomolgus monkeys) …
characterization of human pluripotent hematopoietic colony stimulating factor. Proc. Nad. …

Reversible expansion of primate mast cell populations in vivo by stem cell factor.

SJ Galli, A Iemura, DS Garlick… - The Journal of …, 1993 - Am Soc Clin Investig
… However, the addition of rhSCF and rhIL-3 to interphase cultures ofadult human CD34+
bone marrow cells promotes the growth of multiple hematopoietic lineages including mast …

[HTML][HTML] … blood progenitor cells mobilized by recombinant human stem cell factor and recombinant human granulocyte colony-stimulating factor in nonhuman primates

RG Andrews, RA Briddell, GH Knitter, SD Rowley… - Blood, 1995 - Elsevier
… stem cell factor (SCF) plus rhG-CSF mobilizes increased numbers of peripheral blood progenitor
cells (… No hematopoietic or other growth factors were administered to the animals after …

Stem cell factor is a potent synergistic factor in hematopoiesis

G Morstyn, S Brown, M Gordon, J Crawford, G Demetri… - Oncology, 1994 - karger.com
hematopoiesis involve cell contacts within the hematopoietic … , much of the control of blood
cell formation is mediated by a … of primate mast cell populations in vivo by stem cell factor. J …