Anti-inflammatory actions of the heme oxygenase-1 pathway

MJ Alcaraz, P Fernandez… - Current pharmaceutical …, 2003 - ingentaconnect.com
heme oxygenase 1 (HO-1) exerts protective effects and interferes with a number of stages of
inflammation… a novel target for the treatment of inflammatory diseases. The aim of this article …

Heme oxygenase attenuates allergen-induced airway inflammation and hyperreactivity in guinea pigs

A Almolki, C Taillé, GF Martin, PJ Jose… - … of Physiology-Lung …, 2004 - journals.physiology.org
… -inflammatory effects in several models of pulmonary diseases. HO is induced in airways
Therefore, we evaluated the role of HO on airway inflammation [evaluated by bronchoalveolar …

Nitrosative stress, heme oxygenase-1 expression and airway inflammation during severe exacerbations of COPD

M Tsoumakidou, N Tzanakis, G Chrysofakis… - Chest, 2005 - Elsevier
… The aim of this study was to examine the relationship between airway inflammation,
nitrosative stress, heme-oxygenase expression, and acute severe exacerbations of COPD. …

Effect of heme oxygenase-1 overexpression in two models of lung inflammation

A Zampetaki, T Minamino, SA Mitsialis… - Experimental …, 2003 - journals.sagepub.com
heme oxygenase-1 (HO-1) in the regulation of inflammation. … and bilirubin, downregulate
the inflammatory response by either … in lung epithelium to assess the effect of HO-1 on lung

The role of heme oxygenase-1 in pulmonary disease

LE Fredenburgh, MA Perrella… - … journal of respiratory cell …, 2007 - atsjournals.org
… Similarly, biliverdin administration to rats decreases lung inflammation and proinflammatory
cytokine production, and improves survival after LPS administration (3). In addition to its well-…

Expression of heme oxygenase in human airway epithelial cells

LE Donnelly, PJ Barnes - American journal of respiratory cell and …, 2001 - atsjournals.org
… Furthermore, mediators that are increased in inflammatory diseases such as asthma also …
a mechanism for the increased exhalation of CO observed in airway inflammatory disease. …

[HTML][HTML] Immune regulation of heme oxygenase-1 in allergic airway inflammation

Z Xia, W Zhong - Antioxidants, 2022 - mdpi.com
… -1 (HO-1) is not only a rate-limiting enzyme in heme metabolism but is also … airway
inflammation. HO-1 exerts an anti-inflammation role in different stages of airway inflammation via …

[HTML][HTML] Tissue heme oxygenase-1 exerts anti-inflammatory effects on LPS-induced pulmonary inflammation

FM Konrad, U Knausberg, R Höne, KC Ngamsri… - Mucosal …, 2016 - Elsevier
… Therefore, we investigated the role of nonmyeloid and myeloid HO-1 in a murine model of
lipopolysaccharide (LPS)-induced lung inflammation. We used HO-1 flox/flox mice that lack HO…

Heme oxygenase-1-mediated CD4+ CD25high regulatory T cells suppress allergic airway inflammation

ZW Xia, WW Zhong, LQ Xu, JL Sun… - The Journal of …, 2006 - journals.aai.org
… Asthma is a chronic disorder of the airways, and is characterized by reversible airflow
obstruction and airway inflammation, persistent airway hyperreactivity (AHR), and airway

Anti-asthmatic effects of Angelica dahurica against ovalbumin-induced airway inflammation via upregulation of heme oxygenase-1

MY Lee, CS Seo, JA Lee, NH Lee, JH Kim, H Ha… - Food and Chemical …, 2011 - Elsevier
airway inflammation and suppressed oxidative stress in the OVA-induced asthma model,
partly via induction of heme oxygenase (… a suppressor of airway allergic inflammation, and may …