Heme oxygenase: the key to renal function regulation

NG Abraham, J Cao, D Sacerdoti… - American Journal of …, 2009 - journals.physiology.org
… The molecular mechanisms underlying the anti-inflammatory and antiapoptotic effects of
CO remain to be fully elucidated. However, a number of studies have shown the possible …

[图书][B] Heme oxygenase in biology and medicine

NG Abraham, J Alam, K Nath - 2002 - books.google.com
molecular biological aspects of the control mechanism for regulating heme oxygenase activity…
For the first time, we are describing the significance of the heme oxygenase system and its …

Heme oxygenases: Cellular multifunctional and protective molecules against UV‐induced oxidative stress

SD Chen, XY Wang, MF Nisar, M Lin… - … medicine and cellular …, 2019 - Wiley Online Library
… It is well known that UVA is an oxidative agent, so we mainly focused on the molecular
mechanism of UVA which actives the antioxidant signal pathways which affect the transactivation …

Modulation of endothelial cell apoptosis by heme oxygenase-1-derived carbon monoxide

MP Soares, A Usheva, S Brouard… - … and Redox Signaling, 2002 - liebertpub.com
… It is well established that expression of heme oxygenase-1 (HO-1) acts in a … heme
catabolism into the gas carbon monoxide (CO). In this review, we discuss the possible molecular

Heme oxygenase and the kidney

N Hill-Kapturczak, SH Chang, A Agarwal - DNA and cell biology, 2002 - liebertpub.com
… of the molecular mechanisms underlying transcriptional activation. Experiments using
additional promoter constructs, chromatin structure analysis, and in vivo footprinting are currently …

Differential effects of heme oxygenase isoforms on heme mediation of endothelial intracellular adhesion molecule 1 expression

FA Wagener, JL da Silva, T Farley, T de Witte… - … of Pharmacology and …, 1999 - ASPET
Heme oxygenase activity was measured after 24 h of incubation of HUVECs with inducers
and inhibitors of HO. Results are described as picomoles of bilirubin formed per milligram of …

Mechanism of heme oxygenase-1 gene induction by curcumin in human renal proximal tubule cells

N Hill-Kapturczak, V Thamilselvan… - American Journal …, 2001 - journals.physiology.org
… To elucidate the molecular mechanism of HO-1 induction, we examined the effects of
diferuloylmethane (curcumin), an inhibitor of the transcription factor AP-1. Surprisingly, curcumin by …

A dual role of heme oxygenase-1 in cancer cells

SK Chiang, SE Chen, LC Chang - International journal of molecular …, 2018 - mdpi.com
Heme oxygenase (HO)-1 is known to metabolize heme into biliverdin/bilirubin, carbon
monoxide, and ferrous iron, and it has been suggested to demonstrate cytoprotective effects …

Evidence suggesting that the two forms of heme oxygenase are products of different genes.

I Cruse, MD Maines - Journal of Biological Chemistry, 1988 - Elsevier
heme oxygenase are distinct molecular entities. The findings also suggested that the HO-1
form is the same molecular species as the form of heme oxygenasemolecular mechanism in …

Modulation of inflammation and immune responses by heme oxygenase-1: implications for infection with intracellular pathogens

DL Costa, EP Amaral, BB Andrade, A Sher - Antioxidants, 2020 - mdpi.com
… by the heme oxygenase system … : heme oxygenase-1 (HO-1), whose expression in liver
was upregulated in response to in vivo treatment of rats with chemicals, and heme oxygenase-2 (…