The heme oxygenase system: update 2005
MD Maines - Antioxidants & redox signaling, 2005 - liebertpub.com
… of heme oxygenase (HO). Since then, the phenomenal rate of expansion of the field, which
extends its reach into the very core of many systems, … of the hemeheme oxygenase system in …
extends its reach into the very core of many systems, … of the hemeheme oxygenase system in …
The heme oxygenase system and its functions in the brain.
MD Maines - Cellular and Molecular Biology (Noisy-le-Grand …, 2000 - europepmc.org
… The heme oxygenase (HO) system was identified in the early 1970s as a distinct microsomal
enzyme system that catalyzes formation of bile pigments (Maines and Kappas, 1974). Up to …
enzyme system that catalyzes formation of bile pigments (Maines and Kappas, 1974). Up to …
The heme oxygenase system: a regulator of second messenger gases
MD Maines - Annual review of pharmacology and toxicology, 1997 - annualreviews.org
▪ Abstract The heme oxygenase (HO) system consists of two forms identified to date: the
oxidative stress–inducible protein HO-1 (HSP32) and the constitutive isozyme HO-2. These …
oxidative stress–inducible protein HO-1 (HSP32) and the constitutive isozyme HO-2. These …
Different faces of the heme-heme oxygenase system in inflammation
FA Wagener, HD Volk, D Willis, NG Abraham… - Pharmacological …, 2003 - ASPET
… the significance of heme and heme oxygenase is presented in view of biological and
pathological processes, with special reference to inflammation. In addition, the heme-HO system is …
pathological processes, with special reference to inflammation. In addition, the heme-HO system is …
The heme oxygenase system: past, present, and future
MD Maines - Antioxidants & redox signaling, 2004 - liebertpub.com
… Deliberating a physiological basis for the high-level expression of HO-2 in the brain led to
the proposal that “heme oxygenase in the brain has functions other than heme degradation”(54…
the proposal that “heme oxygenase in the brain has functions other than heme degradation”(54…
Heme oxygenase and the cardiovascular–renal system
NG Abraham, A Kappas - Free Radical Biology and Medicine, 2005 - Elsevier
… The heme–heme oxygenase (HO) system is a regulator of endothelial cell (EC) 1 integrity
and oxidative stress. Heme is the prosthetic group of numerous enzymes and is important to …
and oxidative stress. Heme is the prosthetic group of numerous enzymes and is important to …
The heme oxygenase system: its role in liver inflammation
C Wunder, RF Potter - Current Drug Targets-Cardiovascular & …, 2003 - ingentaconnect.com
… regarding the cytoprotective properties provided by the activity of heme oxygenase (HO), the
rate-limiting enzyme in the degradation of heme. Although particular attention will be paid to …
rate-limiting enzyme in the degradation of heme. Although particular attention will be paid to …
The heme-heme oxygenase system: a molecular switch in wound healing
FA Wagener, HE van Beurden, JW von den Hoff… - Blood, 2003 - ashpublications.org
… heme proteins and heme. Here, we investigated the involvement of heme and its degrading
enzyme heme oxygenase (… We observed that heme directly accumulates at the edges of the …
enzyme heme oxygenase (… We observed that heme directly accumulates at the edges of the …
Heme oxygenase structure and mechanism
PRO de Montellano, A Wilks - 2000 - Elsevier
… The distinct steps in the oxidation of heme to biliverdin catalyzed by heme oxygenase. The
substituted carbons of the porphyrin ring are labeled, as are the mesopositions. The oxygens …
substituted carbons of the porphyrin ring are labeled, as are the mesopositions. The oxygens …
Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications
MD Maines - The FASEB journal, 1988 - Wiley Online Library
… known heme oxygenase, the activity of which can be induced … In this review recent findings
on heme oxygenase … MAINES, MD Heme oxygenase: function, multiplicity, regulatory …
on heme oxygenase … MAINES, MD Heme oxygenase: function, multiplicity, regulatory …