… Here we report hemin transfer from hemin-containing IsdA (holo-IsdA) to hemin-free IsdC
(… During the reaction, holo-IsdA binds to apo-IsdC and then transfers the cofactor to apo-IsdC …

… Oxygen is required in S, aureus for the biosynthesis of hemin and in its absence the … aureus
… It was assumed that hemin is involved in the transfer of an excited state of oxygen to cellular …

… Here, we report that IsdH N2N3 promotes hemin release from both the α- and β-subunits. …
flow transfer assay, we determined the energetics and micro-rate constants of hemin extraction …

… Therefore, we generated a stable mutant in electron transport by interrupting one of the hemin
biosynthetic genes, hemB, in S. aureus … Successful transfer of the ermB cassette into the S. …

… In this report, we examined hemin transfer between the other couples of the human
methemoglobin (metHb), IsdA, IsdB, IsdC, and IsdE system. We found that: 1) metHb directly …

… upregulation of HrtAB upon exposure to hemin suggests that S. … aureus to adapt to hemin
toxicity is likely the result of coordinated changes in protein expression that occur upon hemin …

… Staphylococcus aureus menadione and hemin auxotrophs, … with exogenous menadione
or hemin resulted in rapid growth, … of staphylococcal menadione and hemin auxotrophs and …

… Hemin (Sigma) was dissolved in DMSO for estimation of solution concentrations. Hemin
concentrations in DMSO were calculated using the extinction coefficients 10.74 mm –1 cm –1 at …

… aureus to use DFO in the presence of additional hemin was specific to hydroxamate-type
siderophores, we repeated the same growth experiments; however, exogenous SA and …

… -containing plates of nutrient agar that were transferred on hemin several times accumulated
hemin not significantly less than the original untreated culture. This means that the …