The utility of activated partial thromboplastin time (aPTT) clot waveform analysis in the investigation of hemophilia A patients with very low levels of factor VIII activity …
M Shima, T Matsumoto, K Fukuda… - Thrombosis and …, 2002 - thieme-connect.com
… When aPTT waveform analysis was performed on a number of patients with severe hemophilia
A, we found the waveforms differed from patient to patient despite the fact that all were in …
A, we found the waveforms differed from patient to patient despite the fact that all were in …
Blood coagulation in hemophilia A and hemophilia C
KM Cawthern, C van 't Veer, JB Lock… - Blood, The Journal …, 1998 - ashpublications.org
… aPTT clotting assays indicated that the specific activity of factor XI was unaffected by these
treatments. After FPRck and DFP treatments, analysis of residual factor XIa activity was …
treatments. After FPRck and DFP treatments, analysis of residual factor XIa activity was …
Hemophilia A and B are associated with abnormal spatial dynamics of clot growth
MV Ovanesov, JV Krasotkina, LI Ul'yanova… - … et Biophysica Acta (BBA …, 2002 - Elsevier
… in hemophilia, we compared the spatial dynamics of clotting in platelet-free plasma from
healthy donors and from patients with severe hemophilia … , we determined the APTT in the same …
healthy donors and from patients with severe hemophilia … , we determined the APTT in the same …
… hemostasis potential and aPTT‐clot waveform analysis as powerful laboratory diagnostic tools for identification of hemophilia A patients with unexpected bleeding …
M Milos, D Coen Herak… - … journal of laboratory …, 2021 - Wiley Online Library
… This study emphasizes OHP and aPTT-CWA as a powerful laboratory diagnostic tool in
identifying HA patients with unexpected bleeding presentations, with the best results achieved by …
identifying HA patients with unexpected bleeding presentations, with the best results achieved by …
[HTML][HTML] Whole blood clot formation phenotypes in hemophilia A and rare coagulation disorders. Patterns of response to recombinant factor VIIa
B Sørensen, J Ingerslev - Journal of Thrombosis and Haemostasis, 2004 - Elsevier
… WB clotting profiles amongst patients with severe hemophilia. … the effect of rFVIIa in hemophilia
A and other rare coagulation … In hemophilia A patients with inhibitor antibodies the APTT …
A and other rare coagulation … In hemophilia A patients with inhibitor antibodies the APTT …
[HTML][HTML] Global coagulation assays in hemophilia A: a comparison to conventional assays
S Aghighi, A Riddell, CA Lee, SA Brown… - … Practice in Thrombosis …, 2020 - Elsevier
… hypocoagulability and may be useful in the monitoring of patients with hemophilia. … ) that
made the instrument and APTT reagents used to perform clot waveform measurements in this …
made the instrument and APTT reagents used to perform clot waveform measurements in this …
Clot waveform analysis in patients with haemophilia A
T Siegemund, U Scholz, R Schobess… - …, 2014 - thieme-connect.com
… Patients, method: In this study the feasibility of clot waveform analysis for monitoring of
haemophilia A … The utility of activated partial thromboplastin time (aPTT) clot waveform analysis in …
haemophilia A … The utility of activated partial thromboplastin time (aPTT) clot waveform analysis in …
Update on the clot waveform analysis
H Wada, T Matsumoto, K Ohishi… - … Applied Thrombosis …, 2020 - journals.sagepub.com
… The APTT is a clotting time assay that is useful for diagnosing deficiencies in the coagulation
factors of the intrinsic pathway, such as hemophilia, 6 the presence of inhibitors, such as …
factors of the intrinsic pathway, such as hemophilia, 6 the presence of inhibitors, such as …
[HTML][HTML] The measurement of low levels of factor VIII or factor IX in hemophilia A and hemophilia B plasma by clot waveform analysis and thrombin generation assay
T Matsumoto, M Shima, M Takeyama, K Yoshida… - Journal of thrombosis …, 2006 - Elsevier
… the test citrated plasma sample clots [2]. Thus, clot waveform analysis can be performed at
the same time as the regular clotting end point is determined for the aPTT and PT assays. The …
the same time as the regular clotting end point is determined for the aPTT and PT assays. The …
… ) testing: solutions to establishing and verifying normal reference intervals and assessing APTT reagents for sensitivity to heparin, lupus anticoagulant, and clotting …
EJ Favaloro, G Kershaw… - … in thrombosis and …, 2019 - thieme-connect.com
… APTT is commonplace in patients with severe/moderate hemophilia, a normal APTT may not
exclude mild hemophilia… the sensitivity of the reagent to the particular clotting factor(s). Most …
exclude mild hemophilia… the sensitivity of the reagent to the particular clotting factor(s). Most …
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