… To better understand the link between prophylactic FVIII replacement therapy and bleeding
patterns in patients with severe hemophilia A, the aim of this study was to characterize the …

… plasma samples from 600 healthy individuals stratified by age, sex, … hemophilia A patients
without FVIII inhibitors, 20 hemophilia A patients with inhibitors, and 23 hemophilia A patients …

… treatment centers in the USA collected data on mild and moderate hemophilia patients who
were exclusively treated with on-demand therapy. Patients with inhibitors were excluded. A …

… Individuals with severe hemophilia A are usually diagnosed during the first two years of life
… family history of hemophilia. Without prophylactic treatment, individuals may average up to …

… to individual needs. Whereas PK does not set optimal thresholds or define patient needs,
tailoring treatment to individual characteristics, … of individual PK yields suboptimal results. …

… This report summarizes the clinical characteristics and outcomes of 25 patients with AHA
who were diagnosed, treated, and followed up at a single medical center between 1999 and …

… individual patient characteristics can improve outcomes and be cost–effective in patients with
hemophilia; therefore, hemophilia … individual characteristics Citation[6,7]. In the treatment of …

… with hemophilia and parents of pediatric hemophilia patients in … hemophilia A and B,
suggesting that hemophilia B patients … as hemophilia A patients, despite the fact that hemophilia A …

… We combined individual patient data of all 272 previously untreated patients with severe
hemophilia A (residual FVIII activity <0.02 IU mL −1 ) who had participated in one of four …

… This study describes the association between factor VIII half-life and the clinical
characteristics of patients with severe hemophilia. We found that shorter factor VIII half-life was …