Factor VIII products and inhibitor development in severe hemophilia A

SC Gouw, JG Van Der Bom, R Ljung… - … England Journal of …, 2013 - Mass Medical Soc
… To assess whether our findings were robust, we also compared the incidence of inhibitor
development according to the product brands used at the first exposure to factor VIII (a time-…

Treatment-related risk factors of inhibitor development in previously untreated patients with hemophilia A: the CANAL cohort study

SC Gouw, JG van der Bom… - Blood, The Journal of …, 2007 - ashpublications.org
… even prevent inhibitor development in hemophilia patients. … 13 European and 1 Canadian
hemophilia treatment centers, we … inhibitor development, we plotted the cumulative incidences

Inhibitor development and mortality in non‐severe hemophilia A

CL Eckhardt, JI Loomans… - … of Thrombosis and …, 2015 - Wiley Online Library
Inhibitor development in non-severe hemophilia is associated with increased mortality. High
rates of hemophilia… the impact of inhibitor development on non-severe HA patients. This is …

Risk factors for inhibitor development in severe hemophilia A

I Garagiola, R Palla, F Peyvandi - Thrombosis research, 2018 - Elsevier
… The plasma-derived products containing von Willebrand factor were recently suggested to
determine a lower incidence of inhibitor development than recombinant products in PUPs, in …

[HTML][HTML] Rate of inhibitor development in previously untreated hemophilia A patients treated with plasma‐derived or recombinant factor VIII concentrates: a systematic …

A Iorio, S Halimeh, S Holzhauer, N Goldenberg… - Journal of Thrombosis …, 2010 - Elsevier
… Background: Different rates of inhibitor development after either plasma‐derived (… the
incidence rates of inhibitor development in previously untreated patients (PUPs) with hemophilia A …

Inhibitor development in haemophilia according to concentrate

K Fischer, R Lassila, F Peyvandi… - Thrombosis and …, 2015 - thieme-connect.com
… to assess inhibitor development according to clotting factor concentrate in severe haemophilia
A … The cumulative incidence of inhibitor development in PUPs according to product was …

A sudden increase in factor VIII inhibitor development in multitransfused hemophilia A patients in The Netherlands. Dutch Hemophilia Study Group

FR Rosendaal, HK Nieuwenhuis, HM Van den Berg… - 1993 - ashpublications.org
incidence of inhibitor development among hemophilia A patients in The Netherlands, particularly
among patients … This increased incidence is likely to be associated with the usage of a …

[HTML][HTML] Surgery and inhibitor development in hemophilia A: a systematic review

CL Eckhardt, M VAN DER NAALD, M Peters… - Journal of Thrombosis …, 2011 - Elsevier
Incidence of inhibitor development in patients that received intensive treatment with FVIII
concentrates for surgery was compared with the incidence of inhibitor development in others …

[HTML][HTML] Treatment characteristics and the risk of inhibitor development: a multicenter cohort study among previously untreated patients with severe hemophilia A

SC Gouw, HM Van Den Berg, S Le Cessie… - Journal of Thrombosis …, 2007 - Elsevier
… Although we observed a slightly higher incidence of inhibitors in patients who were first
treated during the first 6 months of life, we did not find a clearly decreasing trend in …

The multifactorial etiology of inhibitor development in hemophilia: genetics and environment

SC Gouw, HM van den Berg - Seminars in thrombosis and …, 2009 - thieme-connect.com
… The incidence rate of inhibitor development in these previously treated patients with hemophilia
A, treated on at least 150 exposure days, has been estimated to be ~2 per 1000 patient-…