Comprehensive landscape of heparin therapy for COVID-19

C Shi, W Tingting, JP Li, MA Sullivan, C Wang… - Carbohydrate …, 2021 - Elsevier
… On the basis of these critical functions of heparin, we illustrate both … heparin therapy has
multiple effects for COVID-19. The therapeutic approach of using heparin to manage COVID-19

Heparin as a therapy for COVID-19: current evidence and future possibilities

JA Hippensteel, WB LaRiviere… - … of Physiology-Lung …, 2020 - journals.physiology.org
… that initiation of heparin for 27 patients infected with COVID-19 improved oxygenation; …
COVID-19 have not yet recommended the use of therapeutic heparin or other forms of therapeutic

[HTML][HTML] Heparin therapy improving hypoxia in COVID-19 patients–a case series

EM Negri, BM Piloto, LK Morinaga, CVP Jardim… - Frontiers in …, 2020 - frontiersin.org
… in COVID-19 patients, and heparin use during in-hospital stay has been associated with
decreased mortality. COVID-19 … Interestingly, in COVID-19, pulmonary compliance is preserved …

[HTML][HTML] Beneficial non-anticoagulant mechanisms underlying heparin treatment of COVID-19 patients

B Buijsers, C Yanginlar, ML Maciej-Hulme… - …, 2020 - thelancet.com
… We propose that therapeutic treatment with heparin/LMWH will interfere with several
pathological processes in COVID-19 patients, thereby increasing their survival rate. …

[HTML][HTML] The versatile heparin in COVID19

J Thachil - Journal of Thrombosis and Haemostasis, 2020 - jthjournal.org
… In summary, there are several ways heparin can prove beneficial in patients with COVID19
(Figure 1). In this respect, the correct dose of LMWH is a matter of immediate interest as a …

Potential of heparin and nafamostat combination therapy for COVID19

H Asakura, H Ogawa - Journal of Thrombosis and Haemostasis, 2020 - jthjournal.org
… of COVID-19. Tang et al reported that heparin (particularly low molecular weight heparin) …
In Japan, anticoagulants used for DIC include heparin as well as antithrombin concentrates, …

Randomized trials of therapeutic heparin for COVID19: a meta‐analysis

M Sholzberg, BR da Costa, GH Tang… - … and practice in …, 2021 - Wiley Online Library
therapeutic heparin is beneficial in moderately ill patients but not in severely ill patients
hospitalized with COVID-19… We included RCTs comparing therapeutic-dose heparin

[HTML][HTML] The association between treatment with heparin and survival in patients with Covid-19

L Ayerbe, C Risco, S Ayis - Journal of thrombosis and thrombolysis, 2020 - Springer
… the treatment with heparin and mortality in patients admitted with Covid-19. Routinely recorded,
clinical data, up to the 24th of April 2020, from the 2075 patients with Covid-19, admitted …

[HTML][HTML] Therapeutic anticoagulation with heparin in noncritically ill patients with Covid-19

ATTACC, ACTIV-4a, and REMAP-CAP … - New England Journal …, 2021 - Mass Medical Soc
… among patients with coronavirus disease 2019 (Covid-19). We hypothesized that
therapeutic-dose … may improve outcomes in noncritically ill patients who are hospitalized with …

[HTML][HTML] Heparin in COVID-19 patients is associated with reduced in-hospital mortality: the multicenter Italian CORIST study

A Di Castelnuovo, S Costanzo… - Thrombosis and …, 2021 - thieme-connect.com
… sample of patients with COVID-19 hospitalized throughout Italy, shows that heparin use was
… support the use of heparin in in-patients with COVID-19, particularly in severely ill patients. …