… of hepatic ischemia-reperfusion injury and analyze the protective strategies; both current and
future options to prevent hepatic … the first two antioxidant enzymes that have been proven to …

Background: The morbidity associated with liver transplantation and major hepatic resections
is partly a result of ischemia-reperfusion injury. Data Sources: The entire world literature on …

… Rac1, a member of the Rho family of small GTPases, regulates this enzyme. Inhibition of …
of neutrophils during the initial reperfusion phase after hepatic ischemia. EC, endothelial cells; …

… Hepatic ischemia reperfusion injury (IRI) is not only a … Hepatic IRI can seriously impair liver
function, even … neutrophils, and NO, are involved in the regulation of hepatic IRI processes. …

… Ischemia/reperfusion (I/R) injury associated with hepatic … the disease mechanisms most
commonly invoked in hepatic I/R injury. The … enzymes chosen to prevent or treat hepatic ischemic …

… enzyme markers raises the issue of whether ischemia per se causes hepatocyte injury, or
whether activation of Kupffer cells is the mechanism of ischemia/reperfusion hepatic injury. …

… enzyme xanthine oxidase (XO) was a major source of the oxidants produced following
reperfusion of the ischemic … in lipid peroxide associated with hepatic ischemia/reperfusion. The …

Ischemia/reperfusion (I/R) injury is a multifactorial process that affects graft function after …
based on the concept that hepatic I/R injury represents a case for a host “innate” immunity. …

… ischemic time for a substantial conversion of the enzyme to … factor in the overall mechanism
of reperfusion injury [6, 101, … minor role during hepatic ischemiareperfusion injury (reviewed …

… This was shown by improved hepatic microcirculation, decreased release of liver enzymes,
enhanced restoration of high-energy phosphates and reduced mortality. Interestingly, in an …