Mechanisms of the free fatty acid-induced increase in hepatic glucose production

TKT Lam, A Carpentier, GF Lewis… - … and Metabolism, 2003 - journals.physiology.org
… that are involved in hepatic lipid and glucose metabolism. It is still unclear, however, how
these molecular events affect the physiology of lipid and glucose metabolism in the liver. …

[HTML][HTML] PGC-1β in the regulation of hepatic glucose and energy metabolism

J Lin, PT Tarr, R Yang, J Rhee, P Puigserver… - Journal of Biological …, 2003 - ASBMB
… play distinct roles in hepatic glucose metabolism. The reduced … associate with and coactivate
hepatic nuclear receptor 4α (… distinct arrays of activities in hepatic energy metabolism. …

Adaptations of hepatic lipid and glucose metabolism in response to high‐macronutrient diets in juvenile grass carp

N Xie, H Wen, SQ Xie, M Jiang, L Yu, F Wu… - Aquaculture …, 2021 - Wiley Online Library
… investigating the hepatic lipid and glucose metabolism of grass … Results showed that the
highest contents of hepatic crude fat, … Data on hepatic mRNA expression indicated that the high-…

Liver steatosis in juvenile obesity: correlations with lipid profile, hepatic biochemical parameters and glycemic and insulinemic responses to an oral glucose tolerance …

G Guzzaloni, G Grugni, A Minocci, D Moro… - International journal of …, 2000 - nature.com
… and glycemic and insulinemic metabolism in young obese are … lipid profile, serum levels
of biochemical hepatic parameters and glycemic and insulinemic responses to an oral glucose

Molecular pathophysiology of hepatic glucose production

K Sharabi, CDJ Tavares, AK Rines… - Molecular aspects of …, 2015 - Elsevier
… By regulating the activity of key glycolytic or gluconeogenic enzymes, the liver can switch
from net hepatic glucose storage to glucose output. Out of the 10 reactions in glycolysis, 7 are …

Effects of fructose on hepatic glucose metabolism in humans

M Dirlewanger, P Schneiter… - … and Metabolism, 2000 - journals.physiology.org
glucose production and elicits only small rises in glycemia (16, 22). We previously proposed
that stimulation of hepatic … were involved in maintaining a constant glucose production (22). …

Zonation of glucose and fatty acid metabolism in the liver: mechanism and metabolic consequences

BS Hijmans, A Grefhorst, MH Oosterveer, AK Groen - Biochimie, 2014 - Elsevier
hepatic metabolic zonation, with a special focus on zonation of glucose and fatty acid
metabolism… Second, the physiological consequences of segregation of metabolic pathways in the …

[HTML][HTML] A link between hepatic glucose production and peripheral energy metabolism via hepatokines

A Abdul-Wahed, A Gautier-Stein, S Casteras… - … metabolism, 2014 - Elsevier
… uptake by peripheral tissues and increased endogenous glucose production. Here we … of
hepatic glucose production positively modulates whole-body glucose and energy metabolism. …

Effect of long‐term treatment with a small‐molecule glucokinase activator on glucose metabolism, lipid profiles and hepatic function

A Nakamura, H Shimazaki, S Ohyama… - Journal of Diabetes …, 2011 - Wiley Online Library
… that GKA was able to improve glucose metabolism in the mice on the HF diet in the long
term without having any harmful effect on lipid profiles or hepatic function. GKA shows potential …

Irisin is regulated by CAR in liver and is a mediator of hepatic glucose and lipid metabolism

L Mo, J Shen, Q Liu, Y Zhang, J Kuang… - Molecular …, 2016 - academic.oup.com
… Furthermore, this work reveals an essential role of irisin in hepatic glucose and lipid
metabolism and provides a potential therapeutic target for the treatment of metabolic disease. …