miR‑146a improves hepatic lipid and glucose metabolism by targeting MED1

K Li, B Zhao, D Wei, W Wang… - International …, 2020 - spandidos-publications.com
… miR-146a improves lipid metabolism in the liver of HFD mice … of glucose metabolism,
we also found that the lipid metabolism was also improved in HFD mice after hepatic miR-146a …

[HTML][HTML] Hepatic expression and cellular distribution of the glucose transporter family

S Karim, DH Adams, PF Lalor - World journal of gastroenterology …, 2012 - ncbi.nlm.nih.gov
… a glucose-depleted state, this glycogen can then be converted back to glucose for fuel with
up to 70% of total hepatic glucose … Situations in which the balance of glucose homeostasis is …

Sweet changes: glucose homeostasis can be altered by manipulating genes controlling hepatic glucose metabolism

JJ Collier, DK Scott - Molecular Endocrinology, 2004 - academic.oup.com
glucose homeostasis through a delicate balance between hepatic glucose uptake and
utilization (HGU) and hepaticglucose metabolism and promotes overall glucose homeostasis. …

Adipocyte lipid chaperone AP2 is a secreted adipokine regulating hepatic glucose production

H Cao, M Sekiya, ME Ertunc, MF Burak, JR Mayers… - Cell metabolism, 2013 - cell.com
glucose production and gluconeogenic activity in primary hepatocytes in vitro and in lean
mice in vivo. In contrast, neutralization of secreted aP2 reduces glucose … to hepatic glucose

Adipose triacylglycerol lipase is a major regulator of hepatic lipid metabolism but not insulin sensitivity in mice

SM Turpin, AJ Hoy, RD Brown, C Garcia Rudaz… - Diabetologia, 2011 - Springer
Hepatic steatosis is the accumulation of TAG in the liver and is a … Hepatic steatosis is strongly
associated with insulin … suppress hepatic glucose production (HGP) and stimulate glucose

Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

S Softic, MK Gupta, GX Wang… - The Journal of …, 2017 - Am Soc Clin Investig
… It remains to be determined whether activation of different transcriptional programs by
glucose and fructose affects hepatic lipid composition or simply the total amount of lipids. …

Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis

K Uyeda, JJ Repa - Cell metabolism, 2006 - cell.com
hepatic ChREBP results in impaired glucose flux through the glycolytic pathway for the
production of pyruvate and lipids… and its role in glucose and lipid metabolism may shed light on “…

Hepatic lipid metabolism in severe human obesity

JG Kral, K Lundholm, P Björntorp, L Sjöström… - Metabolism, 1977 - Elsevier
… in glucose and lipid metabolism of liver slices from normal rats. Proc Sot Exp Biol Med
122:1208, 1966 2. Topping DL, Mayes PA: The immediate effects of insulin and fructose on …

Regulation of hepatic and peripheral glucose disposal

MC Moore, AD Cherrington, DH Wasserman - … Endocrinology & Metabolism, 2003 - Elsevier
… of glucose delivery (the hepatic portal or a peripheral vein) are key determinants of the rate
of net hepatic glucose uptake. Glucose uptake by muscle requires three steps: delivery of …

Effects of altered hepatic lipid metabolism on regulation of hepatic iNOS

J Stanimirovic, M Obradovic, S Zafirovic… - … and Metabolic …, 2015 - search.proquest.com
… It seems that in vivo iNOS plays a key role in the regulation of insulin sensitivity and hepatic
glucose metabolism by FFA [5]. Elevated circulating FFA may exert proinflammatory and …