… specific CD8 cells in the large majority of chronic HBV-infected … Furthermore, HBV-specific
CD8 cells are not only present in … and T cell exhaustion of HBV-specific CD8 cells do not occur …

… Hepatitis B virus infection may alter the activation status and receptor expression … Hepatitis
B virus-specific CD8 + T cells play a major role in controlling and resolving HBV infection. …

… of HBV infection, focusing in particular on the role of CD8 + T cells and … of hepatitis B surface
antigen (HBsAg) expression during chronic infection, possibly triggering dysfunctional T cell …

… CD8 + T cells kill infected cells and secrete antiviral cytokines (mainly interferon [IFN]-γ)
that inhibit HBV replication noncytopathically [4, 5]. Neutralizing antibodies limit …

… of HBV infection in control, CD4-depleted, and CD8-depleted … CD8 + cells are the main
effector cells responsible for viral … acute HBV infection, and they suggest that viral clearance is …

… HBV infection, we attempted to expand CD8 + T cells specific … individuals with chronic HBV
infection were twice stimulated in … of expanded HBV-specific CD8 + T cells was quantified by …

… can affect virus-specific CD8 cells in chronic viral infections. Here we … of CD8 cells present
in chronic hepatitis B virus (HBV) infection which survive in the face of a high quantity of viral …

… The T cell response to the hepatitis B virus (HBV) is vigorous, … acutely infected patients who
successfully clear the virus and … of CD8+ T cells (but not CD4+ T cells) at the peak of infection …

… hepatitis B virus (HBV) infection (CHB) is characterized by a large influx of non–virus-specific
CD8 T cells. … insights into mechanisms of failure of viral control and liver damage in this …

… Longitudinal analysis of HLA-A2-restricted HBV-specific CD8 T cells in resolved and chronic
hepatitis B patients have also revealed that the functional fate of epitope specificities differs …