CD8+ T cell responses specific for hepatitis B virus core protein in patients with chronic hepatitis B virus infection

W Cao, Z Qiu, T Zhu, Y Li, Y Han, T Li - Journal of Clinical Virology, 2014 - Elsevier
CD8+ T cell responses specific for hepatitis B virus core protein in patients with chronic
hepatitis B virus infection - … Hepatitis B virus (HBV) infection is a global health problem. …

Role of hepatitis B virus specific cytotoxic T cells in liver damage and viral control

A Bertoletti, M Maini, R Williams - Antiviral research, 2003 - Elsevier
… In the mouse model of influenza virus infection, efficient virus … at which virus specific CD8
cells expand and exert anti-viral … the lowering of the viral load, viral specific CD8 cells would fall …

… Chain (CD127) on Virus-Specific CD8+ T Cells Identifies Functionally and Phenotypically Defined Memory T Cells during Acute Resolving Hepatitis B Virus Infection

T Boettler, E Panther, B Bengsch, N Nazarova… - Journal of …, 2006 - Am Soc Microbiol
… pathogenesis, viral load, and functional and phenotypical T-cell … the hepatitis B virus (HBV)-specific
CD8 + T-cell response … acutely infected patients who subsequently cleared the virus. …

The size of the viral inoculum contributes to the outcome of hepatitis B virus infection

S Asabe, SF Wieland, PK Chattopadhyay… - Journal of …, 2009 - Am Soc Microbiol
… , for hepatitis B virus (HBV), the size of the inoculum contributes to the kinetics of viral spread
… priming on the influx of HBV-specific CD8 + T cells into the liver of the infected animals, we …

Immunopathogenesis of hepatitis B virus infection

JJ Chang, SR Lewin - Immunology and cell biology, 2007 - Wiley Online Library
… The activation of Kupffer cells via other viral infections, … CD8 + T-cells are the main effector
cells involved in HBV clearance. Depletion of CD8 + T-cells following acute HBV infection of …

[PDF][PDF] Immune-mediated liver injury in hepatitis B virus infection

IS Oh, SH Park - Immune network, 2015 - synapse.koreamed.org
CD8(+) T cells mediate viral clearance and disease pathogenesis during acute hepatitis B
virus infection… induced during chronic hepatitis B virus infection promote a pathway for NK cell-…

Cellular immune response to hepatitis B virus-encoded antigens in acute and chronic hepatitis B virus infection.

C Ferrari, A Penna, A Bertoletti, A Valli… - … (Baltimore, Md.: 1950 …, 1990 - journals.aai.org
… -infected subjects who develop a self-limited acute hepatitis show a vigorous PBMC response
to hepatitis B core Ag and HBeAg, as expression of T cell … ' and CD8' preS2specific T cell

[PDF][PDF] The immunoregulatory role of CD244 in chronic hepatitis B infection and its inhibitory potential on virus‐specific CD8+ T‐cell function

B Raziorrouh, W Schraut, T Gerlach, D Nowack… - …, 2010 - Wiley Online Library
… role in CD8ž T-cell dysfunction during chronic hepatitis B virus infection (HBV) and the in …
T-cell function with the enhancement of proliferation and cytokine release.T-cell restoration by …

Hepatitis B surface antigen could contribute to the immunopathogenesis of hepatitis B virus infection

Y Kondo, M Ninomiya, E Kakazu… - International …, 2013 - Wiley Online Library
… The deletion site (nucleotides 4–57) of Pre S2 has been recognized to correlate with an
epitope of the CD8 T-cell response and B cell neutralization [33]. Therefore, Pre S2 mutants are …

[PDF][PDF] Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection

JN Stoop, RG van der Molen, CC Baan… - …, 2005 - Wiley Online Library
… Chronic hepatitis B virus (HBV) infection is characterized by … T cells (Treg) can suppress the
function of effector T cells and … HBV infection, a multispecific CD4 and CD8 T-cell response …