Innate and adaptive immune responses in hepatitis B virus infection

A Das, MK Maini - Digestive Diseases, 2010 - karger.com
… , we quantitated effector function of global CD8 T cells by flow cytometry. In patients with
chronic hepatitis B, we found a skewing of effector function in all CD8 T cells, regardless of their …

Profile of tumor antigen-specific CD8 T cells in patients with hepatitis B virus-related hepatocellular carcinoma

AJ Gehring, ZZ Ho, AT Tan, MO Aung, KH Lee, KC Tan… - Gastroenterology, 2009 - Elsevier
… T-cell responses to 16 tumor antigens and hepatitis B virus (… Cells from 30 HLA-A2+,
HBV-infected patients (10 with HCC, 10 … control of chronic viral infections such as hepatitis C and …

Hepatitis B virus infection: current status

P Ocama, CK Opio, WM Lee - The American journal of medicine, 2005 - Elsevier
Hepatitis B virus does not cause direct cell injury except in … , both cellular and humoral,
determines the course of infection and the … (CD8+ cells) leads to destruction specific to infected

[HTML][HTML] Immunotherapy for chronic hepatitis B virus infection

A Bertoletti, N Le Bert - Gut and liver, 2018 - ncbi.nlm.nih.gov
… to infection with hepatitis B virus (HBV) and hepatitis C virus (… The two different viruses (HCV
is an RNA virus belonging to … acutely infected with HBV, deletion of CD8 T cells causes the …

Hepatitis B core antigen stimulates interleukin-10 secretion by both T cells and monocytes from peripheral blood of patients with chronic hepatitis B virus infection

N Hyodo, I Nakamura, M Imawari - Clinical & Experimental …, 2004 - academic.oup.com
… In chronic hepatitis B virus (HBV) infection cellular immune … basis for viral persistence in
chronic HBV infection has not … IL-10 production by CD4 + and CD8 + T cells, as well as by …

Longitudinal Analysis of CD8+ T Cells Specific for Structural and Nonstructural Hepatitis B Virus Proteins in Patients with Chronic Hepatitis B: Implications for …

GJM Webster, S Reignat, D Brown, GS Ogg… - Journal of …, 2004 - Am Soc Microbiol
… Due to the functional alterations of CD8 + T cells caused by chronic viral infection (34),
immunological studies performed with single detection methods might underestimate the quantity …

Increased frequency of CD8+ CD45R0+ memory T lymphocytes in acute hepatitis B virus infection

MC Jung, W Schraut, T Santantonio, U Spengler… - Journal of …, 1993 - Elsevier
… response was found in the CD8+CD 45R0 + memory cell population (8). … viral infections
we asked whether CD8+CD45R0 ũ cells may be expanded in acute and chronic hepatitis B

Natural Killer Cells Induce CD8+ T Cell Dysfunction via Galectin-9/TIM-3 in Chronic Hepatitis B Virus Infection

S Liu, C Xu, F Yang, L Zong, Y Qin, Y Gao… - Frontiers in …, 2022 - frontiersin.org
… 9 + than with Gal-9 - NK cells. We showed that in vitro depletion of … cells increased circulating
hepatitis B virus (HBV)-specific CD8 + T cell responses in patients with active CHB infection

Upregulation of the Tim-3/galectin-9 pathway of T cell exhaustion in chronic hepatitis B virus infection

G Nebbia, D Peppa, A Schurich, P Khanna, HD Singh… - PloS one, 2012 - journals.plos.org
cell response in chronic hepatitis B virus infection (CHB). We found Tim-3 to be expressed on
a higher percentage of CD4 and CD8 T cells … T cells and those infiltrating the HBV-infected

[PDF][PDF] Foxp3+ regulatory T cells protect the liver from immune damage and compromise virus control during acute experimental hepatitis B virus infection in mice

L Stross, J Günther, G Gasteiger, T Asen, S Graf… - …, 2012 - Wiley Online Library
CD8 T cells or development of memory T cells. Furthermore, Tregs controlled the recruitment
of innate immune cells such as macrophages and dendritic cells to the infectedinfected