… T lymphocytes, especially on CD8+ T cells, was demonstrated in HBV … CD8+ T cells in
HBV model mice was observed. Very interestingly, we found Tim-3 expression on CD8+ T cells …

… . Hepatitis B virus-specific T cells associate with viral control upon nucleos(t)ide-analogue …
. In situ analysis of intrahepatic virological events in chronic hepatitis B virus infection. J Clin …

… Recent reports have indicated that PD-1 is markedly upregulated on the surface of exhausted
virus-specific CD8 + T cells in mice with lymphocytic choriomeningitis virus infection [11] …

… HBV infection and the CD8+ T cell response. We present the evidence that CD8+ T cells
play an … with chronic hepatitis B virus infection. Hepatology (2005) 41(4):771–8. doi:10.1002/…

… cellular expression of several immunomodulatory molecules, we hypothesized that HBx
expression in hepatocytes might affect CD8+ T cell … several chronic viral infections such as those …

… CD8 + but also of CD4 + T cells for killing virus-infected cells. We investigated 76 patients with
viral hepatitis [15 hepatitis B virus (HBV), 22 HBV/hepatitis … also in other viral infections, we …

… but developed chronic hepatitis B, insufficient CD4 help and defective CD8 repertoire
may have … Hepatitis B virus DNA in serum and blood cells of hepatitis B surface antigen-negative …

… CD14 + monocytes, CD19 + B cells and CD4 + or CD8 + T cells were separated from PBMC
using immunomagnetic beads for the respective surface marker (Miltenyi Biotech). In some …

… Disappearance of HBV RNA and DNA coincided with the influx of intrahepatic CD3 and
CD8 T cell markers (Fig. 1C) and mild increases in serum transaminases (Fig. 1D). …

… Virus-specific CD8 T cells play a major role in viral clearance and disease pathogenesis
during infection with hepatitis B virus (HBV) and hepatitis C virus (… resolution of viral infections. …