Factors predictive of response to interferon-α therapy in hepatitis C virus infection

A Tsubota, K Chayama, K Ikeda, A Yasuji, I Koida… - Hepatology, 1994 - journals.lww.com
interferon-a therapy, we prospectively evaluated 60 consecutive patients with chronic hepatitis
C … Variables related to the hepatitis C virus included genotype and concentration in serum …

Immunoregulatory Cytokines in Chronic Hepatitis C Virus Infection: Pre–and Posttreatment With Interferon Alfa

TV Cacciarelli, OM Martinez, RG Gish, JC Villanueva… - Hepatology, 1996 - journals.lww.com
… Initial diagnosis was made by a positive Hepatitis C virus (HCV) has been …
Significance of serum hepatitis C virus RNA levels in chronic … J hepatitis C. Lancet 1993;341:1501-1504. …

Interferon-α–induced TRAIL on natural killer cells is associated with control of hepatitis C virus infection

…, J Hadem, PV Suneetha, J Jaroszewicz, C Wang… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Pegylated interferon-α (PEG-IFNα), in combination with ribavirin,
controls hepatitis C virus (HCV) infection in approximately 50% of patients by mechanisms that …

Interferonα Therapy for Hepatitis C Virus Infection After Liver Transplantation

TL Wright, C Combs, M Kim, L Ferrell, P Bacchetti… - Hepatology, 1994 - journals.lww.com
hepatitis C virus infection on interferon therapy and that treatment is associated with fall in
hepatitis C virus RNA … Pretreatment variables such as hepatitis C virus RNA levels and serum …

Transcriptional response to hepatitis C virus infection and interferonalpha treatment in the human liver

…, A Suslov, MH Heim, A Necsulea - EMBO molecular …, 2017 - embopress.org
Hepatitis C virus (HCV) infections are a major cause of liver‐related morbidity and mortality.
An estimated 160 million persons are chronically infected worldwide and are at risk to …

A functional SNP of interferon-γ gene is important for interferon-α-induced and spontaneous recovery from hepatitis C virus infection

Y Huang, H Yang, BB Borg, X Su… - Proceedings of the …, 2007 - National Acad Sciences
… are associated with disease outcome and interferon (IFN) treatment response in hepatitis
C virus (HCV) infection. We genotyped eight SNPs spanning the entire IFN-γ gene in two …

Age-related response to interferon alfa treatment in women vs men with chronic hepatitis C virus infection

J Hayashi, Y Kishihara, K Ueno, K Yamaji… - Archives of internal …, 1998 - jamanetwork.com
… alfa is used widely for patients with chronic hepatitis C virus (HCV) infection. Little is known,
however, of the relationship between patients' sex and the effectiveness of interferon alfa …

Hyaluronic acid–gold nanoparticle/interferon α complex for targeted treatment of hepatitis C virus infection

MY Lee, JA Yang, HS Jung, S Beack, JE Choi, W Hur… - ACS …, 2012 - ACS Publications
… ) conjugated interferon α (IFNα) for the clinical treatment of hepatitis C virus (HCV) infection,
… 1 (OAS1) for innate immune responses to viral infection in the liver tissue, which was much …

[PDF][PDF] Immunological aspects of antiviral therapy of chronic hepatitis B virus and hepatitis C virus infections

B Rehermann, A Bertoletti - Hepatology, 2015 - Wiley Online Library
… T-cell responses in acute hepatitis C virus infection and early … toward cytotoxicity in chronic
hepatitis C in an interferon-alfa-… in chronic hepatitis B and chronic hepatitis C virus infections. …

Altered interferon-α-signaling in natural killer cells from patients with chronic hepatitis C virus infection

T Miyagi, T Takehara, K Nishio, S Shimizu, K Kohga… - Journal of …, 2010 - Elsevier
Interferon (IFN)-α, an essential component in therapy against hepatitis C virus (HCV) infection
However, it remains obscure how chronic HCV infection (CHC) modifies intracellular IFN-α