[PDF][PDF] Characteristics of immune response to tumor‐associated antigens and immune cell profile in patients with hepatocellular carcinoma

…, T Seike, T Tamai, N Iida, M Kitahara, T Yamashita… - …, 2019 - Wiley Online Library
immune response of tumor-associated antigen (TAA)–specific T cells and immune cell profile
in … The frequencies of TAAspecific T cells, the expression levels of surface markers on each …

Comprehensive characterization of immunological profiles and clinical significance in hepatocellular carcinoma

P Tao, L Hong, W Tang, Q Lu, Y Zhao, S Zhang… - Frontiers in …, 2021 - frontiersin.org
… In the present study, we used CIBERSORT to quantify the proportions of immune cells in
370 HCC patients based on their immune gene profiling available from public databases, and …

Deviations of the immune cell landscape between healthy liver and hepatocellular carcinoma

…, G Timelthaler, G Oberhuber, M Pinter, T Reiberger… - Scientific reports, 2018 - nature.com
… The obtained immune cell profiles provided enumeration and activation status of 22 immune
cell subtypes. Mast cells were evaluated by immunohistochemistry in ten HCC patients. …

Distinct tumour antigen-specific T-cell immune response profiles at different hepatocellular carcinoma stages

…, N He, P Zhao, Q Wang, X Li, Y Peng, T Dong… - BMC cancer, 2021 - Springer
immune system in controlling HCC progression but also revealed that our understanding of
T cell immune response to HCC is insufficient, especially in terms of diverse T cell immunity

Identification of an immune-specific class of hepatocellular carcinoma, based on molecular features

D Sia, Y Jiao, I Martinez-Quetglas, O Kuchuk… - Gastroenterology, 2017 - Elsevier
… of immune cells that infiltrate hepatocellular carcinomas (… these types of agents might be
effective against liver tumors. … expression profiles from tumor, stromal, and immune cells using a …

[HTML][HTML] Immunology of hepatocellular carcinoma

M Sachdeva, YK Chawla, SK Arora - World journal of hepatology, 2015 - ncbi.nlm.nih.gov
… , macrophages, and T cells), their cytokine profile, and the … of immune cells in hepatocellular
carcinoma. As the disease progresses from cirrhosis of the liver to hepatocellular carcinoma (…

The immunology of hepatocellular carcinoma

M Ringelhan, D Pfister, T O'Connor, E Pikarsky… - Nature …, 2018 - nature.com
cells (NK cells), natural killer T cells (NKT cells), γδ T cells and liver-transiting and/or resident
lymphocytes, with a greater ratio of CD8 + T cells to CD4 + T cellsimmunological profile. It …

Profile of tumor antigen-specific CD8 T cells in patients with hepatitis B virus-related hepatocellular carcinoma

AJ Gehring, ZZ Ho, AT Tan, MO Aung, KH Lee, KC Tan… - Gastroenterology, 2009 - Elsevier
… from HCC patients and might contribute to T-cell exhaustion. Blocking PD-1/PD-L1 increased
the frequency of tumor-specific T cells in HCC patients but did not restore T cell function. …

[HTML][HTML] Use of expression profiles of HBV-DNA integrated into genomes of hepatocellular carcinoma cells to select T cells for immunotherapy

AT Tan, N Yang, TL Krishnamoorthy, V Oei, A Chua… - Gastroenterology, 2019 - Elsevier
… -positive HCC cells to generate epitopes that are recognized by T cells using HBV-specific
T cells and TCR-like antibodies. We then analyzed HBV gene expression profiles of primary …

Global immune characterization of HBV/HCV-related hepatocellular carcinoma identifies macrophage and T-cell subsets associated with disease progression

G Song, Y Shi, M Zhang, S Goswami, S Afridi, L Meng… - Cell discovery, 2020 - nature.com
… cirrhosis among HCC patients in our cohort, which may affect the composition, transcriptional
profile, phenotype and function of immune cells, as well as the presence of donor specific …