Neutrophils as potential therapeutic targets in hepatocellular carcinoma

D Geh, J Leslie, R Rumney, HL Reeves… - Nature Reviews …, 2022 - nature.com
… The success of atezolizumab plus bevacizumab treatment contributed to a shift in systemic
therapies for hepatocellular carcinoma (HCC) towards combinations that include cancer

Hepatocellular carcinoma: molecular pathways and new therapeutic targets

LR Roberts, GJ Gores - Seminars in liver disease, 2005 - thieme-connect.com
… -term outcome of patients with advanced hepatocellular carcinoma. Because of the high
prevalence of liver cirrhosis in hepatocellular carcinoma patients, these approaches must be …

JNK1, a potential therapeutic target for hepatocellular carcinoma

F Chen, K Beezhold, V Castranova - … Acta (BBA)-Reviews on Cancer, 2009 - Elsevier
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide.
Despite tremendous efforts to diagnose and institute new treatment regimens, the prognosis is …

Advances in drug development for hepatocellular carcinoma: clinical trials and potential therapeutic targets

XY Luo, KM Wu, XX He - Journal of Experimental & Clinical Cancer …, 2021 - Springer
Although hepatocellular carcinoma (HCC) is one of the deadliest health burdens worldwide,
few drugs are available for its clinical treatment. However, in recent years, major …

MPHOSPH1: a potential therapeutic target for hepatocellular carcinoma

X Liu, Y Zhou, X Liu, A Peng, H Gong, L Huang, K Ji… - Cancer research, 2014 - AACR
… Here, we show that MPHOSPH1 is overexpressed in hepatocellular carcinoma (HCC)
cells, where it is essential for proliferation. Attenuating MPHOSPH1 expression with a tumor-…

Novel therapeutic targets and predictive markers for hepatocellular carcinoma

SL Chan, AWH Chan, W Yeo - … Opinion on Therapeutic Targets, 2015 - Taylor & Francis
… discuss promising therapeutic target, with focus on those targets with available drugs under
development, for treatment of HCC. We also aim to highlight potential predictive biomarkers …

Cancer stem cell as a potential therapeutic target in hepatocellular carcinoma

R WC Pang, R TP Poon - Current Cancer Drug Targets, 2012 - ingentaconnect.com
… of CSCs, which may be potential therapeutic targets. The role of … therapeutic targets for
CSCs. Conventional cytotoxic drugs kill differentiated cancer cells and cause a reduction in tumor

[HTML][HTML] Novel hepatocellular carcinoma molecules with prognostic and therapeutic potentials

B Scaggiante, M Kazemi, G Pozzato… - World journal of …, 2014 - ncbi.nlm.nih.gov
… HCC markers and therapeutic targets. Keywords: Hepatocellular carcinoma, Biochemical …
observations, miR-372 has been suggested as a potential therapeutic target for HCC[74]. …

Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets

K Schulze, S Imbeaud, E Letouzé, LB Alexandrov… - Nature …, 2015 - nature.com
… to improve tumor characterization to optimize personalized treatment for patients with
hepatocellular carcinoma (HCC). Exome sequencing analysis of 243 liver tumors identified …

Androgen receptor is a new potential therapeutic target for the treatment of hepatocellular carcinoma

WL Ma, CL Hsu, MH Wu, CT Wu, CC Wu, JJ Lai… - Gastroenterology, 2008 - Elsevier
… , but not androgens, as a potential new and better therapeutic target for the battle of HCC. …
the development of hepatocellular carcinoma (HCC), the etiology of this liver cancer remains …