Identification of hepatocellular carcinoma related genes with k-th shortest paths in a protein–protein interaction network

M Jiang, Y Chen, Y Zhang, L Chen, N Zhang… - Molecular …, 2013 - pubs.rsc.org
Hepatocellular carcinoma (HCC) is the most common type of liver cancer worldwide and …
method to identify hepatocellular carcinoma related genes based on k-th shortest paths in the …

Identification of hepatocellular carcinoma–related genes with a machine learning and network analysis

T Gui, X Dong, R Li, Y Li, Z Wang - Journal of Computational …, 2015 - liebertpub.com
shortest path between these two proteins with Dijkstra’s algorithm (Dijkstra, 1959). The shortest
paths … , meaning that there are at least 145 shortest paths going through this gene. This …

Network features suggest new hepatocellular carcinoma treatment strategies

O Lavi, J Skinner, MM Gottesman - BMC systems biology, 2014 - Springer
… to analyze gene expression data from hepatocellular carcinomas of varying responsiveness
and … Second, we explore the redundant short paths between the MAPK and Focal Adhesion …

Hepatitis C virus network based classification of hepatocellular cirrhosis and carcinoma

T Huang, J Wang, YD Cai, H Yu, KC Chou - PloS one, 2012 - journals.plos.org
… proteins by searching the shortest paths between them. The … , cirrhotic, and hepatocellular
carcinoma liver tissue samples … to liver cirrhosis and hepatocellular carcinoma classification. …

Investigation of the roles of trace elements during hepatitis C virus infection using protein-protein interactions and a shortest path algorithm

LC Zhu, XJ Chen, X Kong, YD Cai - Biochimica et Biophysica Acta (BBA) …, 2016 - Elsevier
… Type C hepatitis, as a type of hepatitis, has been reported to induce cirrhosis and hepatocellular
carcinoma within a very short amount of time. It is a great threat to human health. Some …

Identification of hub genes and pathways associated with hepatocellular carcinoma based on network strategy

J Liu, P Hua, L Hui, LL Zhang… - Experimental and …, 2016 - spandidos-publications.com
… Stress centrality is a metric based on the number of nodes in the shortest path between two
other nodes (29). A stressed node was a node traversed by a high number of shortest paths. …

A systematic study of critical miRNAs on cells proliferation and apoptosis by the shortest path

P Xu, Q Wu, D Lu, J Yu, Y Rao, Z Kou, G Fang, W Liu… - BMC …, 2020 - Springer
hepatocellular carcinoma [13]. To link miRNA with human diseases, the Human microRNA
Disease Database (HMDD) curates experiment-supported evidences for human miRNA and …

[HTML][HTML] How hepatitis C virus leads to hepatocellular carcinoma: A network-based study

V Poortahmasebi, M Poorebrahim, S Najafi… - Hepatitis …, 2016 - ncbi.nlm.nih.gov
… The s and t are nodes in the network different from n, σ st indicates the number of shortest
paths from s to t and σ st (n) is the number of shortest paths from s to t that n lies on. …

Deciphering the novel target genes involved in the epigenetics of hepatocellular carcinoma using graph theory approach

N Roy, U Raj, S Rai, PK Varadwaj - Current Genomics, 2019 - ingentaconnect.com
… Where, d (i, j) is the shortest distance between node i and j. • Stress Centrality: For a node
‘a’, the stress centrality is the number of shortest paths passing through ‘a’. Higher the value of …

The role of Hepatitis C Virus in the dynamic protein interaction networks of hepatocellular cirrhosis and carcinoma

T Huang, L Liu, Q Liu, G Ding, Y Tan… - … biology and drug …, 2011 - inderscienceonline.com
… The transformation proteins and HCV target proteins derived from the shortest paths between
cirrhosis and HCC in our study were significantly overlapped with hypergeometric test P …