Polymorphisms of tumor necrosis factor-alpha and hepatocellular carcinoma risk: a HuGE systematic review and meta-analysis

Y Wei, F Liu, B Li, X Chen, Y Ma, L Yan, T Wen… - Digestive diseases and …, 2011 - Springer
… between tumor necrosis factor-alpha (TNFA) polymorphisms and hepatocellular carcinoma
(… Table 2 Stratified analyses of the TNF-alpha polymorphisms on hepatocellular carcinoma (…

The TNF-α, IL-1B and IL-10 polymorphisms and risk for hepatocellular carcinoma: a meta-analysis

Y Yang, C Luo, R Feng, S Bi - Journal of cancer research and clinical …, 2011 - Springer
hepatocellular, cancer or carcinoma, polymorphism or variant or genotype or SNP, and tumor
necrosis factor or TNF-α … a total of 20 articles on TNF-α-308 G/A (n = 13), TNF-α-238 G/A (n …

Clinical aspects of tumor necrosis factor-α signaling in hepatocellular carcinoma

MK Jang, H Su Kim, YH Chung - Current pharmaceutical …, 2014 - ingentaconnect.com
… the TNF-α signaling pathway in hepatocarcinogenesis and the new challenge of TNF-α as
a … Hepatocyte apoptosis is induced via death ligands like TNFα, Fas ligand, and TNF related …

Autotaxin expression and its connection with the TNF-alpha-NF-κB axis in human hepatocellular carcinoma

JM Wu, Y Xu, NJ Skill, H Sheng, Z Zhao, M Yu… - Molecular cancer, 2010 - Springer
… regulation of ATX expression in human hepatocellular carcinoma (HCC) remain elusive. …
TNF-α on the expression of ATX in human liver cell lines. Assessed by QRT-PCR assays, TNF-α

TNF-α is a potential therapeutic target to overcome sorafenib resistance in hepatocellular carcinoma

W Tan, X Luo, W Li, J Zhong, J Cao, S Zhu, X Chen… - …, 2019 - thelancet.com
… The role of tumor necrosis factor alpha (TNF-α) in targeted therapy for hepatocellular carcinoma
… The current study aimed to clarify the mechanistic effects of targeting TNF-α to overcome …

Increased risk of developing hepatocellular carcinoma associated with carriage of the TNF2 allele of the− 308 tumor necrosis factor-α promoter gene

SY Ho, YJ Wang, HL Chen, CH Chen, CJ Chang… - Cancer Causes & …, 2004 - Springer
… between this polymorphism and hepatocellular carcinoma (HCC). Methods: We recruited
74 HCC patients and 289 healthy controls, and determined their )308 TNF-a promoter …

The role of cytokines in hepatocellular carcinoma

A Budhu, XW Wang - Journal of leukocyte biology, 2006 - academic.oup.com
Hepatocellular carcinoma (HCC) is a frequent malignancy worldwide with a high rate of
metastasis. The hepatitis B and C viruses are considered major etiological factors associated …

Human tumor necrosis factor (TNF)-alpha-induced protein 8-like 2 suppresses hepatocellular carcinoma metastasis through inhibiting Rac1

X Cao, L Zhang, Y Shi, Y Sun, S Dai, C Guo, F Zhu… - Molecular cancer, 2013 - Springer
… In present study, we provide evidence that TIPE2 inhibits effectively human hepatocellular
carcinoma metastasis. The forced expression of TIPE2 in HCC-derived cell lines markedly …

TIPE2 inhibits TNF-α-induced hepatocellular carcinoma cell metastasis via Erk1/2 downregulation and NF-κB activation

YH Zhang, HQ Yan, F Wang… - International …, 2015 - spandidos-publications.com
TNF-α have been reported to be involved in liver carcinoma metastasis, the effect of
TIPE2 on hepatocellular carcinoma … We demonstrate that TNF-α clearly augments MMP-13/MMP-3 …

Cross-talk between TNF-α and IFN-γ signaling in induction of B7-H1 expression in hepatocellular carcinoma cells

N Li, J Wang, N Zhang, M Zhuang, Z Zong… - Cancer Immunology …, 2018 - Springer
… In the present study, we asked whether TNF-α can promote the expression of B7-… TNF-α
and IFN-γ in murine HCC cells facilitated tumor growth in vivo. Our findings suggest that TNF-α