… useful than the herpes simplex virus thymidine kinase/ganciclovir (HSV-tk/ … cell death in
human HCC cells in comparison with HSV-tk/GCV, we transduced human HCC cells of the cell …

… selective cytotoxicity of GCV to AFP-producing hepatoma cells in our present study. The 0.3-…
-producing hepatoma cells in this study is that, in AFP-nonproducing hepatoma cells as well …

… for selectively killing AFP-positive hepatocellular carcinoma cell in vitro by AAV-mediated …
hepatocellular carcinoma cells and causes only AFP and albumin-positive hepatoma cells …

… hepatoma cells. An in vitro bystander effect was ob(AFP) promoter/enhancer to direct …
hepatocellular carcinoma cells by adenovivector carrying herpes simplex virus thymidine kinase …

… genes to HCC cells in vitro. We suggest that a gene therapy approach to hepatocellular
carcinoma can be established using adenoviral transfer of HSV-tk to tumor cells and subsequent …

… virus thymidine kinase (HSV-tk) gene. Methods After transfection of a rat hepatoma cell line
… in a TK-expressing cell line and in a control cell line using thymidine (IdA; measured under …

… the herpes simplex virus-thymidine kinase/ganciclovir (TK/GCV) suicide gene system
controlled by the survivin promoter on hepatocellular carcinoma (HCC) cells in vitro. Recombinant …

… produced by these cells (+2tkn cells) was transduced to XC rat hepatoma cells under the …
(XCtkn) cells were selected by culturing under the presence of 500pg/ml of G418. A cell line (…

… from cytosol fraction of rat hepatoma 3924A. The enzyme had … it neutralized the activities of
thymidine kinase from both rat … the amount of cytosol thymidine kinase in hepatomas 16, 7787 …

… vector encoding herpes simplex virus thymidine kinase (HSV-TK) gene (Ad.TK) followed by
systemic ganciclovir to patients with advanced hepatocellular carcinoma (HCC). Secondarily…