Histone deacetylase inhibitor stimulateCYP3A4 proximal promoter activity in hepg2 cells

JY Kim, MR Ahn, DK Kim, YY Sheen - Archives of pharmacal research, 2004 - Springer
… gene expression by proximal promoter in human hepatoma HepG2 cells. Also we have …
of CYP3A4 proximal promoter activity in human hepatoma HepG2 cells. HepG2 cells were …

Ten allelic apolipoprotein [a] 5'flanking fragments exhibit comparable promoter activities in HepG2 cells.

S Bopp, S Köchl, F Acquati, P Magnaghi… - Journal of lipid …, 1995 - Elsevier
… A possible limitation of our analysis comes from the usage of HepG2 cells for the investigation
of apo[a] promoter activities. Although HepG2 cells express many liver-specific gene …

… 204A> C of the cholesterol 7α-hydroxylase gene: Association with response to plant sterols in humans and increased transcriptional activity in transfected HepG2 cells

I De Castro-Orós, S Pampín, M Cofán, P Mozas, X Pintó… - Clinical nutrition, 2011 - Elsevier
… Relative luciferase activity standardized with Renilla activityactivity in HepG2 cells following
transfection of the promoter … A difference between −204A and −204C promoter activity (p …

Increased transcriptional activity of the CYP3A4*1B promoter variant

B Amirimani, B Ning, AC Deitz… - Environmental and …, 2003 - Wiley Online Library
… We evaluated the effect of the variant sequence in the HepG2 and MCF-7 cell lines, and in
primary human hepatocytes from three donors. Reporter constructs with the variant sequence …

Functional analysis of the promoter of human sterol 27-hydroxylase gene in HepG2 cells

R Garuti, MA Croce, L Piccinini, R Tiozzo, S Bertolini… - Gene, 2002 - Elsevier
… core of the HNF4 binding site greatly reduced the promoter activity in HepG2 cells; (ii) the
minimal promoter is transactivated in HeLa cells transfected with a plasmid expressing HNF4. …

Cytokine regulation of low density lipoprotein receptor gene transcription in HepG2 cells

AT Stopeck, AC Nicholson, FP Mancini… - Journal of Biological …, 1993 - ASBMB
… into HepG2 cells, and promoter activity was assayed after TNF and IL- 1 challenge to the
cells. TNF and IL- 1 increased promoter activity 200-400%, while treatment with LDL inhibited …

Activation of the selenoprotein SEPS1 gene expression by pro-inflammatory cytokines in HepG2 cells

Y Gao, NRF Hannan, S Wanyonyi, N Konstantopolous… - Cytokine, 2006 - Elsevier
… α and IL-1β in HepG2 cells [11]. However… promoter and examined the effect of pro-inflammatory
cytokines and ER stress on SEPS1 gene expression and promoter activity in HepG2 cells

Statins Activate Human PPARα Promoter and Increase PPARα mRNA Expression and Activation in HepG2 Cells

M Seo, I Inoue, M Ikeda, T Nakano… - PPAR …, 2008 - Wiley Online Library
… no report that statins activate the human PPARα promoter and transcription of this gene. …
cell line (HepG2 cells). We also investigated the effect of statin treatment on the promoter activity

Transcriptional regulation of the human cholesterol 7 alpha-hydroxylase gene (CYP7A) in HepG2 cells

DP Wang, D Stroup, M Marrapodi, M Crestani… - Journal of lipid …, 1996 - Elsevier
… the promoter activity as measured with luciferase activity ex… the transcriptional activity of
the rat CYP7A in HepG2 cells, … CYP7A transcription in the stable HepG2 cells. As shown in …

Effects of media conditions, insulin, and dexamethasone on insulin-receptor mRNA and promoter activity in HepG2 cells

JR Levy, G Krystal, P Glickman, F Dastvan - Diabetes, 1991 - Am Diabetes Assoc
promoter has multiple transcriptional start sites, the exact location of these sites is somewhat
controversial. We demonstrate in HepG2 cells … that most of the promoter activity is located …