… screening of compounds that inhibit infection of mammalian cells by Trypanosoma cruzi
trypomastigotes. A 2000-compound chemical library was screened using a recombinant …

… of several different heterocyclic cationic compounds, including diamidines … Trypanosoma
cruzi, the etiological agent of Chagas disease. Our present findings showed that all compounds …

Seventy-eight heterocyclic compounds, which included derivatives of furan, isoxazole,
pyridine, pyrrole, and thiophene, were tested in an in vitro system for their antimicrobial activity …

… toxicity of both nitro-heterocyclic compounds, the current recommendations for their use
in CD include the treatment of all acute cases (including transfusion and laboratory-acquired …

… Thus, the goal of this work is the screening of new heterocyclic amidines with the aim of
identifying new compounds with efficacy and selectivity that are equal or superior to those of Bz …

… The evaluation was performed in vitro on cultures of epimastigote and trypomastigote
forms of Trypanosoma cruzi. Some of the tested compounds resulted to be as potent as …

… order Trypanosomatidae include human African trypanosomiasis (HAT) and Chagas disease,
caused by species of Trypanosoma brucei and Trypanosoma cruzi, respectively, as well …

… as biologically active compounds, we designed and synthesized a new series of aryloxy‐quinones,
which were evaluated in vitro against Trypanosoma cruzi in epimastigote form. …

… profile, as a promising compound against Trypanosoma cruzi. SAR analysis also … compounds
C2 and 1g were unable to reduce parasite load, and did not prevent mouse mortality in T…

… The fluorescence of many of these heterocyclic compounds makes it possible to follow their
… forms of Trypanosoma cruzi (A–B) and treated with the heterocyclic compounds for 2 (E–F, I …