Direct Carbon-Hydrogen Bond Functionalization of Heterocyclic Compounds

K Hirano, M Miura - Synlett, 2011 - thieme-connect.com
… for the functionalization of heterocycles have received much attention in organic synthesis. …
and most-reliable processes for the decoration of heterocyclic compounds. [¹] On the other …

Palladium-catalyzed C–N bond formation via direct C–H bond functionalization. Recent developments in heterocyclic synthesis

EM Beccalli, G Broggini, A Fasana… - Journal of Organometallic …, 2011 - Elsevier
… which form a heterocyclic core formally replacing a C–H bond by a C–N bond. Although
several accounts on the use of transition metals in heterocyclic synthesis have been published, …

Construction of Nitrogen‐Containing Heterocycles by C H Bond Functionalization

P Thansandote, M Lautens - Chemistry–A European Journal, 2009 - Wiley Online Library
… focuses on functionalizing pre-existing heterocycles and not on the synthesis of the … This
article will focus on synthetic methodologies that use CH functionalization to construct the …

Multiple-fold C–F bond functionalization for the synthesis of (hetero) cyclic compounds: fluorine as a detachable chemical handle

D Ge, XQ Chu - Organic Chemistry Frontiers, 2022 - pubs.rsc.org
… of single C–F bond. This review … bond functionalization of PFCs for the synthesis of (hetero)cyclic
compounds, especially within the last six years. Easy access to multifarious heterocyclic

An update on direct C–H bond functionalization of nitrogen-containing fused heterocycles

J Aziz, S Piguel - Synthesis, 2017 - thieme-connect.com
… C–H bond functionalization of 5,5- and 6,5-fused heterocycles … C–C bond formation, C–N,
C–S, C–P, and C–Si bonds can … H functionalization approach was applied for the synthesis of …

Exploration of visible-light photocatalysis in heterocycle synthesis and functionalization: reaction design and beyond

JR Chen, XQ Hu, LQ Lu, WJ Xiao - Accounts of chemical research, 2016 - ACS Publications
… (28) In a step toward the construction of potentially bioactive heterocycles, we have also …
of olefin functionalization/cyclization cascade reactions toward heterocyclic synthesis. In this …

Heterocycle Synthesis Based on Palladium-Catalyzed CH Bond Functionalization Methods

R Ferraccioli - Current Organic Synthesis, 2012 - ingentaconnect.com
… the synthesis of benzo-fused heterocycles through Pd-catalyzed carbon−carbon and
carbon−heteroatom bond … recent progress in the synthesis of benzo-fused heterocycles through …

Direct functionalization of nitrogen heterocycles via Rh-catalyzed C− H bond activation

JC Lewis, RG Bergman, JA Ellman - Accounts of chemical …, 2008 - ACS Publications
synthesis of natural products, drug candidates, and other biologically active molecules. In
addition, we developed conditions to directly arylate these heterocyclesbond functionalization

Chiral N‐Heterocyclic Carbene Ligands Enable Asymmetric C− H Bond Functionalization

J Thongpaen, R Manguin… - Angewandte Chemie …, 2020 - Wiley Online Library
… Chiral catalysts: The asymmetric functionalization of C−H bonds is a particularly valuable …
ligands in metal-catalyzed asymmetric C−H bond functionalization is still at an early stage. This …

Recent Advances in Radical C− H Bond Functionalization of Imidazoheterocycles

OPS Patel, NK Nandwana, LJ Legoabe… - Advanced Synthesis …, 2020 - Wiley Online Library
… been developed for alkoxylation, sulfenylation, selenylation and thocyanation of imidazo[1,2-a]pyridines
and related heterocycles based radical C−H bond functionalization reactions.74 …