… the structure‐affinity‐benchmark (SAB, 144 cases with bound/unbound crystal structures
and experimental affinity … First, we present models yielding a marked improvement of affinity …

… the crystal structure of IFN-λ1 bound to its high-affinity receptor IFN-… The crystal structures
were solved using molecular replacement … Since the two structures determined in this work are …

… We present the crystal structure, determined at a resolution of 2.7 A, of the complex … structure
of the uncomplexed form of Src SH2, at a resolution of 2.5 A. We show that the high affinity …

… , exhibits high affinity towards biotin but maintains an inherent dimeric quaternary structure
… loop that plays a crucial role in high-affinity binding and oligomeric stability of the tetrameric …

… is whether proportional affinity gains … high-resolution crystal structure of the complex between
our designed pentavalent ligand and the B pentamer of cholera toxin. The crystal structure …

… , has been slowed by the absence of a high-resolution crystal structure of MK2. Herein we
present a high-resolution (1.9 Å) crystal structure of the highly homologous MK3 in complex …

… high-resolution structure of the Abl-SH3:p41 complex, we discuss the structural determinants
of high affinity … comparison of the crystal structures, we assume that the increased binding …

… We describe here the 2.45-Å resolution x-ray crystal structure of the p50 RHR/RNA aptamer
… crystal structure of the NF-κB p50 RHR homodimer bound to this high-affinity RNA aptamer. …

The design and synthesis of high-affinity FKBP 12 ligands is described. These compounds
potently inhibit the m-rrans-peptidylprolyl isomerase (rotamase) activity catalyzed by FKBP 12 …

… have obtained high-resolution X-ray crystallographic data for … to the heightened divalent
ion affinity. DSC data indicate that … buffer, divalent ion affinity is markedly higher. In 0.15 M KCl …